Phosphodiesterase (PDE)(磷酸二酯酶(PDE))

Phosphodiesterase (PDE) is any enzyme that breaks a phosphodiester bond. Usually, people speaking of phosphodiesterase are referring to cyclic nucleotide phosphodiesterases, which have great clinical significance and are described below. However, there are many other families of phosphodiesterases, including phospholipases C and D, autotaxin, sphingomyelin phosphodiesterase, DNases, RNases, and restriction endonucleases, as well as numerous less-well-characterized small-molecule phosphodiesterases. The cyclic nucleotide phosphodiesterases comprise a group of enzymes that degrade the phosphodiester bond in the second messenger molecules cAMP and cGMP. They regulate the localization, duration, and amplitude of cyclic nucleotide signaling within subcellular domains. PDEs are therefore important regulators ofsignal transduction mediated by these second messenger molecules.

Phosphodiesterase (PDE)(磷酸二酯酶(PDE)) 相关产品（177）

货号	产品名	Cas
PL09694	(R)-(-)-Rolipram	85416-75-7
PL09662	(R)-DNMDP	1630760-60-9
PL09638	(R)-Irsenontrine	1429509-81-8
PC12628	1-(3-氯苯胺基)-4-苯基酞嗪	78351-75-4
PC12753	2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide	107522-19-0
PL09204	AMG 579	1227067-61-9
PC12704	Amino Tadalafil	385769-84-6
PC12501	Aminophylline	317-34-0
PL09653	AN3199	1187187-10-5
PC12483	Apremilast (CC-10004).	608141-41-9
PL09719	Apremilast-d5	1258597-47-5
PL09625	ATX inhibitor 1	2225892-70-4
PL09720	ATX inhibitor 5	2402772-45-4
PL09666	Autotaxin modulator 1	1548743-69-6
PL09665	Autotaxin-IN-3	2156655-68-2
PC12492	Avanafil	330784-47-9
PL09699	Balipodect	1238697-26-1
PL09691	BAY 2666605	2275774-60-0
PL09244	BAY 73-6691	794568-92-6
PL09669	BAY 73-6691 racemate	794568-90-4