COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme that is responsible for formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. Pharmacological inhibition of COX can provide relief from the symptoms of inflammation and pain. Drugs, like Aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years. Two cyclooxygenase isoforms have been identified and are referred to as COX-1 and COX-2. Under many circumstances the COX-1 enzyme is produced constitutively (i.e., gastric mucosa) whereas COX-2 is inducible (i.e., sites of inflammation). Non-steroidal anti-inflammatory drugs (NSAID), such as aspirin and ibuprofen, exert their effects through inhibition of COX. The main COX inhibitors are the non-steroidal anti-inflammatory drugs (NSAIDs).

COX 相关产品（157）

货号	产品名	Cas
PC14389	(+/-)-Sulfinpyrazone	57-96-5
PL05130	(rac)-Etodolac-d3	1276197-46-6
PC14134	(S)-(+)-Ibuprofen	51146-56-6
PL05150	(S)-(+)-Ibuprofen-d3	1329643-44-8
PC14711	(S)-Flurbiprofen	51543-39-6
PC14668	(S)-Ketoprofen	22161-81-5
PC54473	(S)-Ketorolac	66635-92-5
PC14726	(S)-Naproxen.	22204-53-1
PL04329	(±)-Naproxen-d3-1	958293-77-1
PL02792	2-Hydroxy Ibuprofen-d6	1217055-71-4
PL03493	4-Methylamino antipyrine	519-98-2
PC22157	5-A-RU hydrochloride	134452-11-2
PC14723	6-methoxy Naphthalene Acetic Acid	23981-47-7
PC14705	8,11,14-Eicosatriynoic Acid	34262-64-1
PC14675	9,12-Octadecadiynoic Acid	2012-14-8
PC14295	Aceclofenac	89796-99-6
PC14163	Acemetacin	53164-05-9
PL05107	Acetaminophen-d4	64315-36-2
PL05448	Adelmidrol	1675-66-7
PL04443	AG-024322	837364-57-5