MMP

MMPs (Matrix metalloproteinases) are zinc-dependent endopeptidases. The MMPs belong to a larger family of proteases known as the metzincin superfamily. MMPs are capable of degrading all kinds of extracellular matrix proteins, but also can process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands and chemokine/cytokine inactivation. MMPs are also thought to play a major role on cell behaviors such as cell proliferation, migration, differentiation, angiogenesis, apoptosis, and host defense. MMP-2 and MMP-9 are thought to be important in metastasis. MMP-1 is thought to be important in rheumatoid arthritis and osteoarthritis. Recent data suggests active role of MMPs in the pathogenesis of Aortic Aneurysm. Excess MMPs degrade the structural proteins of the aortic wall. Disregulation of the balance between MMPs and TIMPs is also a characteristic of acute and chronic cardiovascular diseases.

MMP 相关产品（65）

货号	产品名	Cas	产品描述
PL07400	(S,S)-TAPI-1	171235-71-5
PL07404	3-Aminopropionitrile fumarate (2:1)	2079-89-2
PL07428	Abametapir	1762-34-1
PL07415	Aderbasib	791828-58-5
PL07425	Apratastat	287405-51-0
PC15696	ARP 100	704888-90-4
PC15697	ARP 101	849773-63-3
PL07416	Batimastat	130370-60-4
PL07398	BI-4394	1222173-37-6
PC79909	Bovine Type II Collagen	9007-34-5	Bovine Type II Collagen (Collagen Type II,Bovine) is a homologous superhelical structure consisting of three identical α1(II) chains, and is a major component of animal cartilage. Type II collagen has a variety of biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and stimulating chondrocyte growth and redifferentiation.
PL07402	Cipemastat	190648-49-8
PC15771	cis-ACCP	777075-44-2
PC15698	CL 82198 hydrochloride	307002-71-7
PL07427	CMC2.24	1255639-43-0
PL07429	Coenzyme Q0	605-94-7
PC15699	CP 471474	210755-45-6
PC15626	CTS-1027	193022-04-7
PL07431	CTTHWGFTLC, CYCLIC TFA
PC15744	DC_AC50	497061-48-0
PL07413	Diethyl-pythiDC	1821370-70-0