Sirtuin

Sirtuin (Sir2 proteins) are a class of proteins that possess either mono-ADP-ribosyltransferase, or deacylase activity, including deacetylase, desuccinylase, demalonylase, demyristoylase and depalmitoylase activity. Sirtuins regulate important biological pathways in bacteria, archaeaand eukaryotes. Sirtuins have been implicated in influencing a wide range of cellular processes like aging, transcription, apoptosis, inflammation and stress resistance, as well as energy efficiency and alertness during low-calorie situations. Sirtuins can also control circadian clocks and mitochondrial biogenesis.

Sirtuin 相关产品（62）

货号	产品名	Cas	产品描述
PL11292	(R)-Selisistat	848193-69-1
PL11296	(S)-Selisistat	848193-68-0
PC54232	(±)-EX-527	49843-98-3
PL11308	3-TYP	120241-79-4
PC10214	4'-bromo-Resveratrol	1224713-90-9
PL08845	7-Chloro-4-(piperazin-1-yl)quinoline	837-52-5
PC54673	AA-861	80809-81-0
PL11293	ADTL-SA1215	782387-91-1
PC10196	AGK 2	304896-28-4	SIRT2抑制剂，AGK2 是一个选择性 SIRT2 抑制剂，其 IC50 值为 3.5 μM。AGK2 也可以抑制 SIRT1 和 SIRT3，且IC50 值分别为 30 和 91 μM。
PC10243	AGK7	304896-21-7
PL09206	AK-1	330461-64-8
PC10140	AK-7	420831-40-9
PC54133	Arachidonic Acid MaxSpec® Standard	506-32-1
PC54135	Arachidonoyl Ethanolamide MaxSpec® Standard	94421-68-8
PC54230	CAY10602	374922-43-7
PC54403	Cl-Amidine (hydrochloride)	1373232-26-8
PC54351	CP 24,879 (hydrochloride)	10141-51-2
PC54654	DAPT	208255-80-5
PL11291	Et-29	2166487-23-4
PC54572	Fingolimod	162359-55-9