mTOR

mTOR (mammalian target of Rapamycin) is a protein that in humans is encoded by the mTOR gene. mTOR is a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription. mTOR belongs to the phosphatidylinositol 3-kinase-related kinase protein family. mTOR integrates the input from upstream pathways, including growth factors and amino acids. mTOR also senses cellular nutrient, oxygen, and energy levels. The mTOR pathway is dysregulated in human diseases, such as diabetes, obesity, depression, and certain cancers. Rapamycin inhibits mTOR by associating with its intracellular receptor FKBP12. The FKBP12-rapamycin complex binds directly to the FKBP12-Rapamycin Binding (FRB) domain of mTOR, inhibiting its activity.

mTOR 相关产品（74）

货号	产品名	Cas
PL07544	(32-Carbonyl)-RMC-5552	2382768-55-8
PL07593	3BDO	890405-51-3
PL07572	Bimiralisib	1225037-39-7
PL07586	Camonsertib	2417489-10-0
PL07581	CC-115 hydrochloride	1300118-55-1
PL07543	CC214-2	1228012-18-7
PL07579	Chromeceptin	331859-86-0
PL07429	Coenzyme Q0	605-94-7
PL07568	CZ415	1429639-50-8
PL07546	DS-7423	1222104-37-1
PL07582	ETP-45658	1198357-79-7
PL07585	ETP-46464	1345675-02-6
PC15449	Everolimus (RAD001).	159351-69-6
PL07590	Everolimus-d4	1338452-54-2
PL07539	FT-1518	1313026-58-2
PL07588	GDC-0349	1207360-89-1
PC15438	GDC-mTOR inhibitor	1207358-59-5
PC15512	GNE-477	1032754-81-6
PL07547	GNE-490	1033739-92-2
PC15511	GNE-493	1033735-94-2