STING

Stimulator of interferon genes (STING) is an integral ER-membrane protein that can be activated by 2'3'-cGAMP synthesized by cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) upon binding of double-stranded DNA. It activates interferon (IFN) and inflammatory cytokine responses to defend against infection by microorganisms.

STING is a key cytosolic receptor for small nucleotides and plays a key role in anticancer and antiviral immunity. STING signaling pathway is also a critical link between innate and adaptive immunity, and induces anti-tumor immune responses. STING agonists, such as endogenous cyclic dinucleotide (CDN) cyclic GMP-AMP (cGAMP), have been used in diverse research for immunogenic tumor clearance, antiviral treatments and vaccine adjuvants.

STING 相关产品（34）

货号	产品名	Cas
PL11525	2',3'-cGAMP sodium
PL11535	ADU-S100 ammonium salt	1638750-96-5
PL11537	ADU-S100 disodium salt	1638750-95-4
PL11538	C-176	314054-00-7
PL11529	C-178	329198-87-0
PL11526	c-di-AMP diammonium
PL11530	c-di-AMP disodium	2734909-87-4
PL11513	ChX710	2438721-44-7
PL11519	Cyclic-di-GMP disodium	2222132-40-1
PL11521	diABZI STING agonist-1	2138299-33-7
PL11533	diABZI STING agonist-1 trihydrochloride	2138299-34-8
PL11518	diABZI-C2-NH2	2137975-93-8
PL11517	E7766 diammonium salt	2242635-03-4
PL11539	H-151	941987-60-6
PL11511	IACS-8803 diammonium
PL11520	IACS-8803 disodium	2243079-36-7
PL07806	JAK-IN-23
PL11536	MSA-2	129425-81-6
PL11527	MSA-2 dimer	2377881-92-8
PL11532	Omaveloxolone	1474034-05-3