Phosphatase

Phosphatases are enzyme that remove a phosphate group from a protein. Protein tyrosine phosphatases (PTPs) comprise a diverse family of transmembrane and cytoplasmic enzymes. PTPs play an important role in regulating the proliferative activity of cells and the integrity of cell-cell and cell-matrix contacts. Protein tyrosine phosphatase 1B (PTP1B) is a non-receptor PTP frequently associated with the endoplasmic reticulum and vesicles subjacent to the plasma membrane. PTP1B as a key negative regulator of leptin receptor pathways has been an attractive therapeutic target for the treatment of type 2 diabetes mellitus and obesity. Four major serine/threonine-specific protein phosphatase catalytic subunits are present in the cytoplasm of animal cells. Three of these enzymes, PP1, PP2A, and PP2B, are members of the same gene family, while PP2C appears to be distinct.The alkaline phosphatases comprise a heterogeneous group of enzymes that are widely distributed in mammalian cells. Acid phosphatase enzymes catalyze the hydrolysis of phosphate monoesters following the general equation.

Phosphatase 相关产品（101）

货号	产品名	Cas
PL09566	(1S,2S,3R)-DT-061	1809427-20-0
PL09593	3α-Aminocholestane	2206-20-4
PL09533	5-FAM-Alkyne	510758-19-7
PL09570	5MPN	47208-82-2
PL09536	6-Hydroxybenzbromarone	152831-00-0
PL09583	7-BIA	1313403-49-4
PL09591	ABBV-CLS-484	2489404-97-7
PL09613	AMPPD	122341-56-4
PL09608	AQX-016A	849669-54-1
PL09555	ARL67156 triethylamine
PL09577	ARL67156 trisodium hydrate
PL09599	Batoprotafib	1801765-04-7
PL09594	BCI	1245792-51-1
PL09620	BCI hydrochloride	95130-23-7
PL09589	BCI-215	1245792-67-9
PL09537	Bis(maltolato)oxovanadium(IV)	38213-69-3
PL09541	BN82002	396073-89-5
PL09564	BN82002 hydrochloride	1049740-43-3
PL09584	BTdCPU	1257423-87-2
PL09534	Calcium glycerophosphate	27214-00-2