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Bcl-2 Family

Bcl-2 is a family of evolutionarily related proteins. These proteins govern mitochondrial outer membrane permeabilization (MOMP) and can be either pro-apoptotic (Bax, Bad, Bak and Bok among others) or anti-apoptotic (including Bcl-2 proper, Bcl-xL, and Bcl-w, among an assortment of others). There are a total of 25 genes in the Bcl-2 family known to date. Human genes encoding proteins that belong to this family include: Bak1, Bax, Bal-2, Bok, Mcl-1.

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PL04928 A-1155463 1235034-55-5
PL02696 A-1210477 1668553-26-1
PL04936 A-1331852 1430844-80-6
PL04579 A-385358 406228-55-5
PL03969 ABBV-167 1351456-78-4
PC54493 ABT-263 923564-51-6
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PL04752 Alofanib 1612888-66-0
PL05315 Amiloride hydrochloride 2016-88-8
PL01476 Aminopurvalanol A 220792-57-4
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