Amyloid-β（β淀粉样蛋白）

Amyloid-β (Aβ) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of theamyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is being cut by certain enzymes to yield Aβ. Amyloid-β molecules can aggregate to form flexible soluble oligomers which may exist in several forms. Amyloid-β peptide is due to overproduction of Aβ and/or the failure of clearance mechanisms. Amyloid-β self-aggregates into oligomers, which can be of various sizes, and forms diffuse and neuritic plaques in the parenchyma and blood vessels. Amyloid-β oligomers and plaques are potent synaptotoxins, block proteasome function, inhibit mitochondrial activity, alter intracellular Ca2+levels and stimulate inflammatory processes. Loss of the normal physiological functions of Aβ is also thought to contribute to neuronal dysfunction.

Amyloid-β（β淀粉样蛋白）相关产品（86）

货号	产品名	Cas
PC14702	(R,S)-Anatabine (tartrate)
PC14701	(R,S)-Anatabine(solution)	2743-90-0
PL13256	2-Hydroxy-5-(phenyldiazenyl)benzoic acid-d5	1331662-16-8
PL13254	4-(6-Bromo-2-benzothiazolyl)benzenamine	566169-97-9
PL09319	Aducanumab	1384260-65-4
PL13275	Aftin-4	866893-90-5
PL08758	Aleplasinin	481629-87-2
PC14029	amyloid A protein fragment [Homo sapiens]
PC14037	Amyloid Beta-Peptide (1-40) (human)	131438-79-4
PC14036	Amyloid Beta-Peptide (12-28) (human)	107015-83-8
PL13270	amyloid P-IN-1	1819986-22-5
PC14025	Amyloid Peptide (25-35) (human)	131602-53-4
PC14015	Amyloid Precursor C-Terminal Peptide
PC14024	Amyloid β-Peptide (10-20) (human)	152286-31-2
PC14014	Amyloid β-Protein (1-15)	183745-81-5
PL07665	Anatabine dicitrate
PL13286	Anle138b	882697-00-9
PC14664	ARN2966	102212-26-0
PL13264	AZD4694 Precursor	1211333-20-8
PL09422	Azeliragon	603148-36-3

Amyloid-β（β淀粉样蛋白）

Amyloid-β（β淀粉样蛋白） 相关产品（86）

Amyloid-β（β淀粉样蛋白）相关产品（86）