RARs

The nuclear retinoic acid receptors (RARs) are transcriptional transregulators, which control the expression of specific gene subsets subsequently to ligand binding and to strictly controlled phosphorylation processes. RARs consist of three subtypes, α (NR1B1), β (NR1B2) and γ (NR1B3), encoded by separate genes. RARs function as ligand-dependent transcriptional regulators, heterodimerized with retinoid X receptors (RXRs), which also consist of three types, α NR2B1, β (NR2B2) and γ (NR2B3). RARs play critical roles in a variety of biological processes, including development, reproduction, immunity, organogenesis and homeostasis, as assessed by vitamin A-deficiency (VAD), pharmacological and genetic studies conducted in the mouse.

Retinoid X receptor (RXR) belongs to a family of ligand-activated transcription factors that regulate many aspects of metazoan life. A class of nuclear receptors requires RXR as heterodimerization partner for their function.

RARs 相关产品（21）

货号	产品名	Cas
PC15252	AC 261066	870773-76-5
PC15197	AC 55649	59662-49-6
PC14753	Adarotene	496868-77-0
PC15238	BMS 195614	253310-42-8
PC15226	BMS 453	166977-43-1
PC15231	BMS 493	215030-90-3
PC15063	BMS 753	215307-86-1
PC15227	BMS 961	185629-22-5
PC15200	CD 1530	107430-66-0
PC15070	CD 2314	170355-37-0
PC15243	CD 2665	170355-78-9
PC15183	CD 437	125316-60-1
PC15193	Ch 55	110368-33-7
PC15245	ER 50891	187400-85-7
PC15194	LE 135	155877-83-1
PC15384	Luffariellolide	111149-87-2
PC15244	MM 11253	345952-44-5
PC14799	Talarozole	201410-53-9
PC14800	Tamibarotene	94497-51-5
PC14879	Tretinoin (Aberela).	302-79-4