iGluR

iGluR (ionotropic glutamate receptor) is a ligand-gated ion channel that is activated by the neurotransmitter glutamate. iGluR are integral membrane proteins compose of four large subunits that form a central ion channel pore. Sequence similarity among all known glutamate receptor subunits, including the AMPA, kainate, NMDA, and δ receptors.

AMPA receptors are the main charge carriers during basal transmission, permitting influx of sodium ions to depolarise the postsynaptic membrane. NMDA receptors are blocked by magnesium ions and therefore only permit ion flux following prior depolarisation. This enables them to act as coincidence detectors for synaptic plasticity. Calcium influx through NMDA receptors leads to persistent modifications in the strength of synaptic transmission.

iGluR 相关产品（93）

货号	产品名	Cas
PL01924	(Rac)-NMDAR antagonist 1	2435557-99-4
PL01133	(RS)-AMPA monohydrate	76463-67-7
PL04647	(S)-(-)-5-Fluorowillardiine hydrochloride	1321546-70-6
PL02725	(S)-Willardiine	21416-43-3
PL05570	6-Methoxy-2-naphthoic acid	2471-70-7
PL03577	AMPA receptor modulator-2	2034181-36-5
PL02524	AMPA receptor modulator-3	211311-39-6
PL01335	Apimostinel	1421866-48-9
PL04345	Becampanel	188696-80-2
PL03023	BPAM344	1204572-55-3
PL06162	Budipine	57982-78-2
PL05336	Bupivacaine	38396-39-3
PL05337	Bupivacaine hydrochloride	18010-40-7
PL02484	BZAD-01	305339-41-7
PL01572	Caroverine hydrochloride	55750-05-5
PL02735	CMPDA	380607-77-2
PL03885	CX 717	867276-98-0
PL01789	CX516-d10	1286653-21-1
PL01828	CX614	191744-13-5
PL05015	Cycloleucine	52-52-8