Wnt信号

The Wnt signaling pathways are a group of signal transduction pathways made of proteins that pass signals from outside of a cell through cell surface receptors to the inside of the cell. Three Wnt signaling pathways have been characterized: the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. All three Wnt signaling pathways are activated by the binding of a Wnt-protein ligand to a Frizzled family receptor, which passes the biological signal to the protein Dishevelled inside the cell. The canonical Wnt pathway leads to regulation of gene transcription, the noncanonical planar cell polarity pathway regulates the cytoskeleton that is responsible for the shape of the cell, and the noncanonical Wnt/calcium pathway regulates calcium inside the cell. The clinical importance of Wnt signaling pathway has been demonstrated by mutations that lead to a variety of diseases, including breast and prostate cancer, glioblastoma, type II diabetes.

Wnt信号相关产品（42）

货号	产品名	Cas	产品描述
PL13194	ABC99	2331255-53-7
PL13214	Adavivint	1467093-03-3
PL13188	Carboxylesterase-IN-2
PL13186	Carboxylesterase-IN-3
PL13202	CWP232228	1144044-02-9
PL13199	DK419	2102672-22-8
PL11840	EMT inhibitor-1	1638526-21-2
PL09924	ETC-159	1638250-96-0
PL10052	FH535	108409-83-2
PL13190	FIDAS-3	1266684-01-8
PL13213	Foxy-5 TFA
PL13203	Fz7-21 TFA
PL13193	FzM1	1680196-54-6
PL13201	FzM1.8	2204290-85-5
PL13211	Hematein	475-25-2
PL10010	Hexachlorophene	70-30-4
PL13208	iCRT3	901751-47-1
PL13210	Ipivivint	1481617-15-5
PL09921	IWP-O1	2074607-48-8
PC54727	IWR-1-endo	1127442-82-3	IWR-1是端锚聚合酶抑制剂，抑制Wnt/β-catenin信号传导途径。

Wnt信号

Wnt信号 相关产品（42）

Wnt信号相关产品（42）