PKA

PKA (Protein kinase A) is a Ser/Thr phosphoryl transferase that transfers the γ-phosphate group of ATP to protein substrates. PKA phosphorylates more than 100 cytoplasmic and membrane associated targets. PKA mediates a myriad of cellular signaling events and its activity is tightly regulated both in space and time.

PKA is an evolutionarily conserved negative regulator of the hedgehog (Hh) signal transduction pathway. PKA is known to be required for the proteolytic processing event that generates the repressor forms of the Ci and Gli transcription factors that keep target genes off in the absence of Hh.

PKA 相关产品（22）

货号	产品名	Cas
PL09862	8-Chloro-cAMP	41941-56-4
PC11845	8-CPT-Cyclic AMP (sodium salt)	93882-12-3
PL09871	A-3 hydrochloride	78957-85-4
PL09870	AT13148	1056901-62-2
PL09717	Bucladesine calcium	938448-87-4
PL09868	CCG215022	1813527-81-9
PC11829	cGMP Dependent Kinase Inhibitor Peptide	82801-73-8
PL09865	CREBtide	149155-45-3
PC11785	H 89 2HCl	130964-39-5
PC11841	H-8 (hydrochloride)	113276-94-1
PL09864	Jaspamycin	22242-96-2
PC11826	KT 5720	108068-98-0
PL09863	Malantide	86555-35-3
PL09869	Midostaurin-d5
PC11744	PKA inhibitor fragment (6-22) amide	121932-06-7
PL09872	PKA Inhibitor Fragment (6-22) amide TFA
PL09873	PKA-IN-1	179985-52-5
PC11831	PKI 14-22 amide, myristoylated	201422-03-9
PL09866	PKI 14-22 amide,myristoylated TFA
PL09867	Rp-cAMPS sodium salt	142439-94-9