c-Kit

c-Kit (Mast/stem cell growth factor receptor, SCFR or CD117) is a proteinthat in humans is encoded by the KIT gene. c-Kit (CD117) is an important cell surface marker used to identify certain types of hematopoietic(blood) progenitors in the bone marrow. c-Kit is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. Altered forms of this receptor may be associated with some types of cancer. c-Kit is a receptor tyrosine kinase type III, which binds to stem cell factor. When c-Kit binds to stem cell factor (SCF) it forms adimer that activates its intrinsic tyrosine kinase activity, that in turn phosphorylates and activates signal transduction molecules that propagate the signal in the cell. Signalling through c-Kit plays a role in cell survival, proliferation, and differentiation.

c-Kit 相关产品（38）

货号	产品名	Cas
PL03433	AC710	1351522-04-7
PL01338	Amuvatinib	850879-09-3
PL01245	Avapritinib	1703793-34-3
PL04785	AZD2932	883986-34-3
PL02108	AZD3229	2248003-60-1
PL02109	AZD3229 Tosylate	2248003-71-4
PL04093	Bezuclastinib	1616385-51-3
PL04391	c-Kit-IN-1	1225278-16-9
PL04797	c-Kit-IN-5-1	1003311-62-3
PL03108	Cabozantinib-d6	1802168-46-2
PL02675	Chiauranib	1256349-48-0
PL01340	Dovitinib lactate	692737-80-7
PL04398	Elenestinib	2505078-08-8
PL03807	Flumatinib	895519-90-1
PC16093	Imatinib (STI571).	152459-95-5
PL04437	Imatinib-d3 (hydrochloride)	1134803-18-1
PL04436	Imatinib-d4	1134803-16-9
PL04435	Imatinib-d8	1092942-82-9
PC16170	ISCK03	945526-43-2
PL04380	KG5	877874-85-6