Triiodothyronine.|6893-02-3|(三碘甲状腺原氨酸; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3)-陌孚医药/Medlife

您当前的位置：

Triiodothyronine. (Synonyms: 三碘甲状腺原氨酸; Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3)

目录号: PC19132 纯度: 99%+

CAS No. :6893-02-3

商品编号	规格	价格	会员价	是否有货	数量
PC19132-25mg	25mg	¥360.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Triiodothyronine.
中文别名	甲碘安;甲碘胺;3,3',5-三碘-L-甲腺原氨酸;碘苯丙氨酸;碘噻罗宁;3,3',5-三碘代-L-甲腺原氨酸;三碘甲状腺原氨酸(甲状腺素T3);3,3',5-三碘甲状腺原氨酸;O-(4-羟基-3-碘苯基)-3,5-二碘-L-酪氨酸;三碘甲状腺原氨酸;3,3',5-三碘代-L-甲状腺原氨酸;3,3'',5-三碘-L-甲腺原氨酸;3,3',5-Triiodo-L-thyronine 3,3',5-三碘-L-甲腺原氨酸;碘塞罗宁;甲状腺激素T3;三碘甲腺原氨酸;3,3',5-三;3,3',5-三碘-L<;3,3’,5-三碘-L-甲状腺氨酸（怕热）;O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸;small>-甲腺原氨酸;碘噻罗宁(T3)标准品;3,3′,5-三碘代-L-甲状腺原氨酸
英文名称	Triiodothyronine
英文别名	(S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoic acid;L-3,3,5-Triiodothyronine, Free Acid;liothyronine;Triiodothyronine;L-triiodothyronine;3,3’,5-triiodothyronine;3,5,3’-triiodothyronine;3’,5-triiodo-l-thyronin;4-(3-iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine;5-diiodophenyl)-3-(4-(4-hydroxy-3-iodophenoxy)-l-alanin;cytomel;l-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine;l-liothyronine;3,3',5-Triiodo-L-thyronine;3,3’,5-Triiodo-L-thyronine;3,3′,5 Triiodothyronine (T3);3,3′,5-Triiodo-L-thyronine (T3) solution;3,5,3′-Triiodo-L-thyronine;3,5,3'-Triiodo-L-thyronine;3,3',5 TRIIODOTHYRONINE (T3), IRMM STANDARD;3,3',5'-TRIIODO-L-THYRONINE;L-3,3',5-Triiodothyronine;L-3,3',5-TRIIODOTHYRONINE, FREE ACID;L-TYROSINE,O-(4-HYDROXY-3-IODOPHENYL)-3,5-DIIODO-;O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine;T3, O-(4-HYDROXY-3-IODOPHENYL)-3,5-DIIODO-L-TYROSINE;Tresitope;三碘甲状腺原氨酸;T3;Liothyronin;3,5,3'-triiodothyronine;triothyrone;Lyothyronine;Liothyroninum;Liotironina;L-T3;3,3',5-Triiodothyronine;Triiodo-L-thyronine;3,5,3'TRIIODOTHYRONINE;L-3,5,3'-Triiodothyronine;(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid;T3 (amino acid);T3 (Hormone)
Cas No.	6893-02-3
分子式	C₁₅H₁₂I₃NO₄
分子量	650.97
包装储存	4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

生物活性

Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with K_is of 2.33 nM for hTRα and hTRβ, respectively.

性状

Solid

IC50 & Target[1][2]

Human Endogenous Metabolite

体外研究(In Vitro)

Liothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine promotes growth, induces differentiation and regualtes metabolic effects.

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transportation.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

ClinicalTrial

结构分类

Ketones, Aldehydes, Acids

参考文献

[1]. Lin KH, et al. Stimulation of proliferation by 3,3,5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94. [Information]

[2]. Bhat MK, et al. Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3,5-triiodo-L-thyronine. Biochem Biophys Res Commun. 1993 Aug 31;195(1):385-92. [Information]

[3]. Hiroaki Shiohara, et al. Discovery of novel indane derivatives as liver-selective thyroid hormone receptor β (TRβ) agonists for the treatment of dyslipidemia. Bioorg Med Chem. 2012 Jun 1;20(11):3622-34. [Information]

溶解度数据

体外研究:

1M NaOH : 50 mg/mL (76.81 mM; ultrasonic and warming and heat to 60°C)

配制储备溶液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.5362 mL	7.6808 mL	15.3617 mL
5 mM	0.3072 mL	1.5362 mL	3.0723 mL
10 mM	0.1536 mL	0.7681 mL	1.5362 mL

产品不同，其溶解度不同。建议根据产品选择合适的溶剂配制储备溶液；配成溶液后，建议分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时，建议在 6 个月内使用，-20°C 储存时，建议在 1 个月内使用。

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation