您当前的位置：

Thymidine. (Synonyms: 胸苷; DThyd; NSC 21548)

目录号: PC10393 纯度: ≥98%

CAS No. :50-89-5

商品编号	规格	价格	会员价
PC10393-5g	5g	¥415.00	请登录
PC10393-10g	10g	¥650.00	请登录
PC10393-25g	25g	¥986.00	请登录
PC10393-100g	100g	¥1550.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称

Thymidine.

中文别名

β-胸腺嘧啶核苷;胸苷;β-胸苷;β-胸苷(dT);2′-脱氧胸苷;2’-脱氧胸苷;2’-脱氧胸苷（胸腺嘧啶核苷）;2'-脱氧胸苷;beta-胸苷;Thymidine 胸苷;β-胸苷标准品;β-胸苷技术转让;β-雄苷;齐多夫定相关物质D USP标准品;胸腺嘧啶核苷;胸腺嘧啶脱氧核苷;1-(2-脱氧-β-D-呋喃核糖)-5-甲基尿嘧啶;2′-脱氧胸腺嘧啶核苷;2p-脱氧胸苷;beta-胸甙;Thymidine β-胸苷;β-胸腺嘧啶核苷,2'-脱氧胸腺嘧啶核苷,胸苷,2'-脱氧胸苷,胸腺嘧啶核苷;齐多呋定杂质E(EP) 标准品;去氧胸腺苷;司他呋啶杂质C(EP);脱氧胸苷;胸腺啶;胸腺核苷;胸腺脱氧核苷;1-(2-脱氧-β-D-呋喃核糖)胸苷;2'-脱氧胸腺嘧啶核苷;[ "胸腺嘧啶核苷" ]

英文名称

Thymidine

英文别名

Thymidine;(1-[2-Deoxy-beta-D-ribofuranosyl]-5-methyluracil);2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-;2'-Deoxythymidine;5-Methyldeoxyuridine;beta-D-Ribofuranoside,thymine-1,2-deoxy-;Deoxythymidine;Dexoythymidine;DThyd;Thymine-2-desoxyriboside;Thyminedeoxyriboside;Uridine,2'-deoxy-5-methyl-;Beta-Thymidine;β-Thymidine;ß-Thymidine;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydro-furan-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-.β.-D-erythro-pentofuranosyl)-5-methyl-;THYMIDIN(RG);1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluraci;1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil;1-(2-Deoxy-β-D-ribofuranosyl)thymine;2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-.Beta.-D-erythro-pentofuranosyl)-5-methyl;2'-dT;b-Thymidine;DTHD;dT;SS-THYMIDINE;Thymidin;Thymine-2-deoxyriboside;Zidovudine Related Compound D;1-(2-Deoxy-beta-D-ribofuranosyl)-5-methyluracil;1-(2-Deoxy-beta-D-ribofuranosyl)thymine;dT;Thymine deoxyriboside;5-Methyl-2'-deoxyuridine;5-Methyldeoxyurindine;Uridine, 2'-deoxy-5-methyl-;1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione;Deoxyribothymidine;2'-thymidine;beta-D-Ribofuranoside, thymine-1 2-deoxy-

Cas No.

50-89-5

分子式

C₁₀H₁₄N₂O₅

分子量

242.23

包装储存

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

生物活性

Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

性状

Solid

IC50 & Target[1][2]

DNA Synthesis

Human Endogenous Metabolite

Microbial Metabolite

体内研究(In Vivo)

Thymidine (500 mg/kg; i.p.; twice a day) completely reverses both Methotrexate- and Tomudex-induced deletion of both CD4Vβ8 and CD8Vβ8 T cells .

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	8-12 weeks BALB/c mice
Dosage:	500 mg/kg
Administration:	i.p.; twice a day
Result:	Completely abrogates Methotrexate- and Tomudex-induced deletion of Vβ8 T cells after SEB injection.

运输条件

Room temperature or refrigerated transportation.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

ClinicalTrial

结构分类

Others

参考文献

[1]. Chen G, et al. Cell Synchronization by Double Thymidine Block. Bio Protoc. 2018 Sep 5;8(17). [Information]

[2]. FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5.FIRKET H, et al. Autoradiographic visualization of synthesis of deoxyribonucleic acid in tissue culture with tritium-labelled thymidine. Nature. 1958 Jan 24;181(4604):274-5. [Information]

[3]. Izeradjene K, et al. Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independentdeletion of superantigen-reactive peripheral T cells. Int Immunol. 2001 Jan;13(1):85-93. [Information]

溶解度数据

体外研究:

DMSO : 50 mg/mL (206.42 mM; Need ultrasonic)

H₂O : 33.33 mg/mL (137.60 mM; Need ultrasonic)

配制储备溶液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.1283 mL	20.6415 mL	41.2831 mL
5 mM	0.8257 mL	4.1283 mL	8.2566 mL
10 mM	0.4128 mL	2.0642 mL	4.1283 mL

产品不同，其溶解度不同。建议根据产品选择合适的溶剂配制储备溶液；配成溶液后，建议分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，建议在 6 个月内使用，-20°C 储存时，建议在 1 个月内使用。

体内研究:

建议根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都建议先按照 体外研究 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

建议依照次序添加每种溶剂： PBS
Solubility: 20 mg/mL (82.57 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关文献

相关产品

The molarity calculator equation

The dilution calculator equation