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Amyloid β-Protein (1-15) (Synonyms: Amyloid β-Protein (1-15))
目录号: PC14014 纯度: ≥98%
CAS No. :183745-81-5
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PC14014-25mg 25mg ¥3773.00 请登录
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中文名称
Amyloid β-Protein (1-15)
中文别名
Β淀粉样蛋白(1-15);Β淀粉样肽(1-15)
英文名称
Amyloid β-Protein (1-15)
英文别名
L-Glutamine, L-a-aspartyl-L-alanyl-L-a-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-a-aspartyl-L-serylglycyl-L-tyrosyl-L-a-glutamyl-L-valyl-L-histidyl-L-histidyl-;H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-OH;Amyloid β -Protein (1-15);AMYLOID BETA-PROTEIN (1-15);L-Glutamine, L-a-aspartyl-L-alanyl-L-a-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-a-aspart...;L-Glutamine, L-a-aspartyl-L-alanyl-L-a-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-a-aspartyl-L-serylglycyl-L-tyrosyl-L-a-;AMyloid b-Protein (1-15);CID 138107641;β-Amyloid 1-15;Amyloid ;L-alpha-Aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutamine
Cas No.
183745-81-5
分子式
C78H107N25O27
分子量
1826.84
包装储存

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*该产品在溶液状态不稳定,建议您现用现配,即刻使用。

生物活性

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimers disease (AD) patients.

性状

Solid

IC50 & Target[1][2]

Amyloid-β

体外研究(In Vitro)

β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. .

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transportation.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*该产品在溶液状态不稳定,建议您现用现配,即刻使用。

SequenceShortening

DAEFRHDSGYEVHHQ

Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln

参考文献
溶解度数据
体外研究: 

H2O : 50 mg/mL (27.37 mM; Need ultrasonic)

配制储备溶液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.5474 mL 2.7370 mL 5.4739 mL
5 mM 0.1095 mL 0.5474 mL 1.0948 mL
10 mM 0.0547 mL 0.2737 mL 0.5474 mL
*

建议根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备溶液;该产品在溶液状态不稳定,建议您现用现配,即刻使用

搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2