您当前的位置:
Ac-DEVD-AMC(solution)
目录号: PC17673 纯度: ≥98%
CAS No. :169332-61-0
商品编号 规格 价格 会员价 是否有货 数量
PC17673-10mg (solution) 10mg (solution) ¥2866.50 请登录
PC17673-5mg (solution) 5mg (solution) ¥1579.76 请登录
PC17673-1mg (solution) 1mg (solution) ¥573.30 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
中文名称
Ac-DEVD-AMC(solution)
中文别名
4-硝基吲哚-2-甲酸;AC-ASP-GLU-VAL-ASP-7-氨基-4-甲基香豆素;7荧光底物AC-DEVD-AMC 蓝;CASPASE 3/7荧光底物AC-DEVD-AMC 蓝;APOPAIN SUBSTRATE;AC-ASP-GLU-VAL-ASP-AMC;胱天蛋白酶CASPASE 3/7荧光底物AC-DEVD-AMC 蓝
英文名称
Ac-DEVD-AMC(solution)
英文别名
L-a-Asparagine, N-acetyl-L-a-aspartyl-L-a-glutamyl-L-valyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;AC-DEVD-AMC;N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin;Ac-Asp-Glu-Val-Asp-AMC;Apopain Substrate;4-[(2-acetamido-3-carboxypropanoyl)amino]-5-[[1-[[3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;AC-ASP-MET-GLN-ASP-AMC: AC-DMQD-AMC;Ac-Devd;AC-DMQD-AMC;AC-DEVD-MCA;ACETYL-DEVD-AMC;AC-ASP-MET-GLN-ASP-AMC;AC-ASP-GLU-VAL-ASP-MCA;AC-DEVD-AMC AMMONIUM SALT;CASPASE-3 FLUOROGENIC SUBSTRATE;CASPASE 3;AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-7-AMINO-4-METHYLCOUMARIN;AC-ASP-GLU-VAL-ASP-AMC AMMONIUM SALT;Ac-DEVD-AMC
Cas No.
169332-61-0
分子式
C30H37N5O13
分子量
675.64
包装储存

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

生物活性

Ac-DEVD-AMC is the Caspase-3 fluorescent substrate.

性状

Solid

体外研究(In Vitro)

Ac-DEVD-AMC is the caspase-3 substrate and could be used to monitor intracellular caspase-3 activity.
The AMC moiety is highest at 2 h (area?=5.6±1.8), the AMC peak area for Ac-DEVD-AMC incubated without lung specimen (substrate alone) for 6 h is relatively small.

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transportation.

储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

SequenceShortening

Ac-DEVD-7-amido-4-Methylcoumarin

Sequence

N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-Methylcoumarin

Emission(Em)
参考文献
溶解度数据
体外研究: 

H2O : 0.67 mg/mL (0.99 mM; Need ultrasonic)

体内研究:

建议根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都建议先按照 体外研究 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    建议依照次序添加每种溶剂: PBS

    Solubility: 3.33 mg/mL (4.93 mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在 Medlife 网站选购。
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2