Thalidomide-O-amido-PEG3-C2-NH2 TFA
目录号: PC22171 纯度: 99.82%

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

CAS No. :1957236-21-3
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中文名称
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文名称
Thalidomide-O-amido-PEG3-C2-NH2 TFA
英文别名
Thalidomide-O-amido-PEG3-C2-NH2 TFA;Thalidomide-O-amido-PEG3-C2-NH2 (TFA);N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]-2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetamide;2,2,2-trifluoroacetic acid;Conjugates 14;TQP0425;BCP30509;Cereblon Ligand-Linker Conjugates 3 (TFA);N-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ac;E3 Ligase Ligand-Linker Conjugates 14
Cas No.
1957236-21-3
分子式
C25H31F3N4O11
分子量
620.53
包装储存
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
产品详情
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
储存方式
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
参考文献

1.BRADNER, James, et al. METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES. WO2017024317A2.

溶解度数据
DMSO: 50 mg/mL (80.58 mM), Sonication is recommended.
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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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