53-79-2|(S)-2-氨基-N-((2S,3S,4R,5R)-5-(6-(二甲胺基)-9H-嘌呤-9-基)-4-羟基-2-(羟甲基)四氢呋喃-3-基)-3-(4-甲氧基苯基)丙酰胺|抑制剂|Medlife

您当前的位置：

(S)-2-氨基-N-((2S,3S,4R,5R)-5-(6-(二甲胺基)-9H-嘌呤-9-基)-4-羟基-2-(羟甲基)四氢呋喃-3-基)-3-(4-甲氧基苯基)丙酰胺嘌呤霉素, Puromycine, NSC-3055, NSC3055, NSC 3055

目录号: PC22164 纯度: 98%

Puromycin (NSC-3055) is an antibiotic protein synthesis inhibitor. It inhibits protein synthesis by binding to RNA. It also serves as an anticancer drug by suppressing the growth and metastasis in esophagus cancer cells by Akt phosphorylation. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.

CAS No. :53-79-2

商品编号	规格	价格	会员价
PC22164-5mg	5mg	¥220.00	请登录
PC22164-50mg	50mg	¥1905.00	请登录
PC22164-100mg	100mg	¥2966.00	请登录
PC22164-250mg	250mg	¥5042.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	(S)-2-氨基-N-((2S,3S,4R,5R)-5-(6-(二甲胺基)-9H-嘌呤-9-基)-4-羟基-2-(羟甲基)四氢呋喃-3-基)-3-(4-甲氧基苯基)丙酰胺
中文别名	嘌呤霉素;嘌呤霉素二盐酸盐水合物;嘌呤霉素二盐酸盐水合物(嘌呤霉素);嘌呤霉素二盐酸盐水合物,MERCK
英文名称	PUROMYCIN
英文别名	PUROMYCIN;(s)-3’-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3’-deoxy-n,n-dimethy;1-mm;3’-(alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyl-adenosinl;3’-(l-alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyladenosine;6-dimethylamino-9-(3’-(p-methoxy-l-phenylalanylamino)-beta-d-ribofuranosyl)-;achromycin;achromycin(purinederivative);Adenosine,3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-;CL13900;PUROMYCIN(RG);p-638;Stylomycin;Adenosine,3'-(a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-,L- (8CI);Adenosine,3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-,(S)-;3'-(a-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine;6-Dimethylamino-9-[3-deoxy-3-(p-methoxy-L-phenylalanylamino)-b-D-ribofuranosyl]-b-purine;P 638;Stillomycin;b-D-Ribofuranoside,6-(dimethylamino)-9H-purine-9 3-deoxy-3-[(4-methoxy-L-phenylalanyl)amino]-;9-{3-deoxy-3-[(O-methyl-L-tyrosyl)amino]-beta-D-xylofuranosyl}-N,N-dimethyl-9H-purin-6-amine;3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-diemthyladenosine;(S)-3'-((2-Amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyladenosine;Achromycin;puromycin;3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine;Puromycin;1-MM;3123L;Achromycin(purine derivative);CL 13900
Cas No.	53-79-2
分子式	C₂₂H₂₉N₇O₅
分子量	471.51
包装储存	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.

产品详情	Puromycin (NSC-3055) is an antibiotic protein synthesis inhibitor. It inhibits protein synthesis by binding to RNA. It also serves as an anticancer drug by suppressing the growth and metastasis in esophagus cancer cells by Akt phosphorylation. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
储存方式	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
参考文献	1.Guo X, Duan Y, Ye X, Hu L, Xu T, Tong L, Yu M. Stable silencing of dll4 gene suppresses the growth and metastasis of esophagus cancer cells by attenuating Akt phosphorylation. Oncol Rep. 2018 May 8. doi: 10.3892/or.2018.6427. [Epub ahead of print] PubMed PMID: 29749499. 2.Yik-Sham Chung C, Timblin GA, Saijo K, Chang CJ. Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining. J Am Chem Soc. 2018 May 3. doi: 10.1021/jacs.8b02279. [Epub ahead of print] PubMed PMID: 29722974. 3.Ahmad F, Salahuddin M, Alsamman K, Herzallah HK, Al-Otaibi ST. Neonatal maternal deprivation impairs localized de novo activity-induced protein translation at the synapse in the rat hippocampus. Biosci Rep. 2018 Apr 26. pii: BSR20180118. doi: 10.1042/BSR20180118. [Epub ahead of print] PubMed PMID: 29700212. 4.Argüello RJ, Simoes MR, Mendes A, Camosseto V, Torres AG, de Pouplana LR, van de Pavert SA, Gatti E, Pierre P. SunRiSE: measuring translation elongation at single cell resolution by flow cytometry. J Cell Sci. 2018 Apr 26. pii: jcs.214346. doi: 10.1242/jcs.214346. [Epub ahead of print] PubMed PMID: 29700204. 5.Han W, Zhang C, Shi C, et al. Roles of eIF3m in the tumorigenesis of triple negative breast cancer[J]. Cancer Cell International. 2020, 20: 1-16

溶解度数据	DMSO: 100 mg/mL (143.72 mM)

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation