DSPE-MPEG(2000) is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095). Formulations containing DSPE-MPEG(2000) have been used in the synthesis of liposomes for the delivery of anticancer and antimalarial agents.1,2,3
性状
A solid
运输条件
冷藏运输。
储存方式
-20°C
参考文献
1. Hasan, G.M., Garg, N., Dogra, E., et al. Inhibition of the growth of Plasmodium falciparum in culture by stearylamine-phosphatidylcholine liposomes. J. Parasitol. Res. 120462 (2011).
2. Rathore, S.S., and Ghosh, P.C. Effect of surface charge and density of distearylphosphatidylethanolamine-mPEG-2000 (DSPE-mPEG-2000) on the cytotoxicity of liposome-entrapped ricin: Effect of lysosomotropic agents. Int. J. Pharm. 350(1-2), 79-94 (2008).
3. Haghiralsadat, F., Amoabediny, G., Helder, M.N., et al. A comprehensive mathematical model of drug release kinetics from nano-liposomes, derived from optimization studies of cationic PEGylated liposomal doxorubicin formulations for drug-gene delivery. Artif. Cells Nanomed. Biotechnol. 46(1), 169-177 (2018).