α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors.
性状
Solid
体外研究(In Vitro)
α2β1 Integrin Ligand Peptide (DGEA) TFA (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity.α2β1 Integrin Ligand PeptideTFA induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM.α2β1 Integrin Ligand Peptide TFA loses its ability to inhibit SA11 binding at 1.0 mM. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisture and lightPowder -80°C 2 years;-20°C 1 year
SequenceShortening
DGEA
Sequence
Asp-Gly-Glu-Ala
参考文献
[1]. Graham KL, et al. Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences. J Virol. 2004 Nov;78(21):11786-97.
溶解度数据
In Vitro: H2O : 33.33 mg/mL (66.08 mM; Need ultrasonic)配制储备液