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Angiotensin I/II (1-6) (TFA)

目录号: PL14750 纯度: ≥98%

商品编号	规格	价格	会员价
PL14750-5mg	5mg	¥865.45	请登录
PL14750-10mg	10mg	¥1483.64	请登录
PL14750-50mg	50mg	询价	询价
PL14750-100mg	100mg	询价	询价

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中文名称	Angiotensin I/II (1-6) (TFA)
英文名称	Angiotensin I/II (1-6) (TFA)
包装储存	Sealed storage, away from moisture and lightPowder -80°C 2 years；-20°C 1 year

产品详情	Angiotensin I/II (1-6) TFA 含有 1-6 个氨基酸，由血管紧张素 I/II 肽转化而来。前体血管紧张素原被肾素裂解形成 Angiotensin I。Angiotensin I 被血管紧张素转换酶 (ACE)水解形成具有生物活性的 angiotensin II。Angiotensin II 用于高血压、肾素-血管紧张素系统和特发性膜性肾病的研究。
生物活性	Angiotensin I/II (1-6) TFA contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
性状	Solid
体外研究(In Vitro)	Angiotensin II is a naturally occurring octapeptide hormone component of the renin-angiotensin-aldosterone system (RAAS) and is a potent vasoconstrictor. Angiotensin II has important roles in cardiovascular, neurologic, and renal physiology, including maintenance of blood pressure, thirst sensation, response to the baroreceptor reflex, determination of renal blood flow and glomerular filtration rate, and electrolyte and free water homeostasis. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisture and lightPowder -80°C 2 years；-20°C 1 year
SequenceShortening	DRVYIH
Sequence	Asp-Arg-Val-Tyr-Ile-His
参考文献	[1]. Erd?s EG, et al. Conversion of angiotensin I to angiotensin II. Am J Med. 1976 May 31;60(6):749-59. [2]. Busse LW, et al. Clinical Experience With IV Angiotensin II Administration: A Systematic Review of Safety. Crit Care Med. 2017;45(8):1285-1294. [3]. Angiotensin II.

溶解度数据	In Vitro: H₂O : 100 mg/mL (109.18 mM; Need ultrasonic)DMSO : ≥ 100 mg/mL (109.18 mM)

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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