Triphala (Synonyms: 三果宝)
目录号: PL14574
CAS No. :857906-76-4
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中文名称
Triphala
中文别名
三果宝;化合物 T13205
英文名称
Triphala
英文别名
Triphala;The combination of fruits of three medicinal plants: Terminalia bellirica, Phyllanthus embilica, and Terminalia chebula (Himalaya Drug Co., Bangalore, India)
Cas No.
857906-76-4
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
Triphala 是阿育吠陀的多草药配方,Triphala 由三种草本植物 Terminalia chebula,Terminalia bellerica,和 Phyllanthus emblica 组成。Triphala 抑制 NF-κB 活化。Triphala 发挥抗真菌 (antifungal) 作用。具有抗脂肪形成,抗炎,抗肿瘤效果。
生物活性
Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica. Triphala inhibits NF-κB activation. Triphala exerts antifungal action. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities.
性状
Solid
IC50 & Target[1][2]
NF-κB Antifungal
体外研究(In Vitro)
Triphala regulates adipogenesis through modulation of expression of adipogenic genes in 3T3-L1 cell line. Triphala significantly decreases the adipogenesis in 3T3-L1 cells by reducing lipid accumulation and inhibiting the expression of adipogenic genes. The 3T3-L1 cells treated with Triphala show ~1.43-, 1.67-, and 2.5-fold decreases in lipid content at 1, 10, and 100 μg/mL concentrations, respectively, compared to the cells treated with induction cocktail alone. Triphala regulates lipid accumulation by down regulating expression of adipogenic genes, resulting into prevention of adipogenesis.
Triphala reduces expression of inflammatory mediators such as IL-17, COX-2, and RANKL through inhibition of NF-κB activation. Triphala exerts antifungal action against Asperigillus species and has been reported to inhibit the fungus by up to 37.96% in vitro.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
ClinicalTrial
结构分类
Others
来源
  • Plants
参考文献
[1]. Banjare J, et al. Triphala, Regulates Adipogenesis through Modulation of Expression of Adipogenic Genes in 3T3-L1 Cell Line. Pharmacogn Mag. 2018 Jan;13(Suppl 4):S834-S839.
[2]. Peterson CT, et al. Therapeutic Uses of Triphala in Ayurvedic Medicine. J Altern Complement Med. 2017 Aug;23(8):607-614.
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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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