CX516-d10|1286653-21-1|-陌孚医药/Medlife

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CX516-d10

目录号: PL14520

CAS No. :1286653-21-1

商品编号	规格	价格	会员价	是否有货	数量
PL14520-1mg	1mg	询价	询价
PL14520-10mg	10mg	询价	询价

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中文名称	CX516-d10
英文名称	CX516-d10
英文别名	Ampalex-d10
Cas No.	1286653-21-1
分子式	C₁₄H₁₅N₃O
分子量	241.29
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	CX516-d₁₀ 是 CX516 的氘代物。CX516 (BDP 12) 是一种 AMPA 受体正向调节剂，可用于阿尔茨海默病，精神分裂等的研究。
生物活性	CX516-d 10 is the deuterium labeled CX516. CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimers disease, schizophrenia and mild cognitive impairment (MCI)[1].
IC50 & Target[1][2]	AMPA Receptor
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Broberg BV, Glenth?j BY, Dias R, et al. Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting. Psychopharmacology (Berl). 2009 Nov;206(4):631-40.

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