Gadobutrol (Synonyms: 钆布醇; ZK 135079)
目录号: PL14026 纯度: ≥99%
CAS No. :770691-21-9
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中文名称
Gadobutrol
中文别名
钆布醇
英文名称
Gadobutrol
英文别名
Gadobutrol
Cas No.
770691-21-9
分子式
C18H31N4O9Gd
分子量
604.71
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
Gadobutrol (Gd-DO3A-butrol; ZK 135079)是一种非离子顺磁性大环钆基造影剂,可用作磁共振成像(MRI)。
生物活性
Gadobutrol (Gd-DO3A-butrol; ZK 135079) is a nonionic paramagnetic macrocyclic gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI).
性状
Solid
体外研究(In Vitro)
Gadobutrol leads to a gradual decrease in cell density with increasing concentration under neutron irradiation.
has not independently confirmed the accuracy of these methods. They are for reference only.Cell Viability Assay
体内研究(In Vivo)
Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice.
has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
ClinicalTrial
参考文献
[1]. B Hofmann, et al. Gadolinium neutron capture therapy (GdNCT) of melanoma cells and solid tumors with the magnetic resonance imaging contrast agent Gadobutrol. Invest Radiol. 1999 Feb;34(2):126-33.
[2]. Takashi Watanabe, et al. Gadobutrol enhances T1-weighted MRI of nerve cells. Toxicol Lett. 2019 Jun 15;308:17-23.
[3]. Cheng KT. Gadobutrol. Molecular I
溶解度数据
In Vitro: H2O : 20 mg/mL (33.07 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2