Diphenylterazine|344940-63-2|(DTZ)-陌孚医药/Medlife

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Diphenylterazine (Synonyms: DTZ)

目录号: PL13140 纯度: ≥98%

CAS No. :344940-63-2

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PL13140-1mg	1mg	¥1854.55	请登录
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PL13140-10mg	10mg	¥5810.91	请登录
PL13140-50mg	50mg	¥12116.36	请登录
PL13140-100mg	100mg	询价	询价
PL13140-200mg	200mg	询价	询价

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中文名称	Diphenylterazine
中文别名	2-苄基-6,8-二苯基咪唑并[1,2-a]吡嗪-3(7H)-酮
英文名称	Diphenylterazine
英文别名	Diphenylterazine;2-Benzyl-6,8-diphenyl-3,7-dihydroimidazo[1,2-a]pyrazine-3-one
Cas No.	344940-63-2
分子式	C₂₅H₁₉N₃O
分子量	377.44
包装储存	-80°C, protect from light, stored under nitrogen

产品详情	Diphenylterazine (DTZ) 是一种生物发光剂。Diphenylterazine 本身仅产生很少的背景，导致极好的信噪比。
生物活性	Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios.
性状	Solid
体外研究(In Vitro)	Diphenylterazine elicits minimal cell toxicity at millimolar concentrations. Notes: To make a stock solution for DTZ (Diphenylterazine), first, a premixture is prepared by dissolving 17.6 mg of L-ascorbic acid (HY-B0166) in 10 mL ethanol and 10 mL 1,2-propanediol; next, 1 mg of DTZ is dissolved in 88 μL of the premix, resulting in a 30 mM DTZ stock solution containing 5 mM L-ascorbic acid. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics. DTZ (0.3 μmol/mouse (1.13 mg.ml/100 ul/mouse); i.v.) treatment can track tumor growth in a xenograft NU/J mouse model. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-80°C, protect from light, stored under nitrogen
参考文献	[1]. Yeh HW, et al. Red-shifted luciferase-luciferin pairs for enhanced bioluminescence imaging. Nat Methods. 2017 Oct;14(10):971-974. [2]. Hsien-Wei Yeh, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019 May 17;14(5):959-965. [3]. Practical Notes for teLuc-DTZ a

溶解度数据	In Vitro: DMSO : 100 mg/mL (264.94 mM; Need ultrasonic; DMSO can inactivate Diphenylterazines activity)DMF : 11.11 mg/mL (29.44 mM; Need ultrasonic; DMSO can inactivate Diphenylterazines activity)EtOH+HCl : 1 mg/mL (2.65 mM; ultrasonic and warming and adjust pH to 2 with 1M HCl and heat to 80°C; DMSO can inactivate Diphenylterazines activity)H₂O : < 0.1 mg/mL (insoluble

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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