Dansylcadaverine
目录号: PL13130 纯度: ≥98%
CAS No. :10121-91-2
商品编号 规格 价格 会员价 是否有货 数量
PL13130-50mg 50mg ¥618.18 请登录
PL13130-100mg 100mg ¥989.09 请登录
PL13130-200mg 200mg 询价 询价
PL13130-500mg 500mg 询价 询价
PL13130-10mM*1mLinDMSO 10mM*1mLinDMSO ¥816.00 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
中文名称
Dansylcadaverine
中文别名
丹酰尸胺;1-氯异喹啉-6-甲醛;N-(5-氨基戊基)-5-(二甲基氨基)萘-1-磺酰胺;5-二甲基氨基萘-1-(n-(5-氨基戊基))磺酰胺;N-丹酰-1,5-戊二胺;丹酰戊二胺;DANSYL 尸胺
英文名称
Dansylcadaverine
英文别名
1-Naphthalenesulfonamide,N-(5-aminopentyl)-5-(dimethylamino)-;Dansylcadaverine;Dansylcadaverine [N-(5-Aminopentyl)-5-dimethylaminonaphthalen-1-sulfonamide];Monodansyl cadaverine;N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide;N-(5-AMINO-PENTYL)-5-DI-METHYL-AMINO-NAPHTHA-LENE-1-SULFON-AMIDE;N-(DIMETHYL-AMINO-NAPHTHA-LENE-SULFONYL)-1;N-(5-Amino­pentyl)-5-di­methyl­amino­naphtha­lene-1-sulfon­amide;N-(Dimethyl­amino­naphtha­lene­sulfonyl)-1,5-pentane­diamine;N-(5-Aminopentyl)-5-(dimethylamino)naphthalene-1-sulphonamide
Cas No.
10121-91-2
分子式
C17H25N3O2S
分子量
335.46
包装储存
-20°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
产品详情
Dansylcadaverine (Monodansyl cadaverine) 是一种用于标记自噬空泡的自荧光化合物。Dansylcadaverine 是谷氨酰胺转胺酶的高亲和力底物,能阻断受体介导的多种配体的内吞作用。
生物活性
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands.
性状
Solid
体外研究(In Vitro)
The inhibitory activity of dansylcadaverine reflects its ability to serve as a substrate for transglutaminases and to block competitively the crosslinking of fibrin molecules.
Dansylcadaverine, a cationic fluorescent probe binds to bacterial lipopolysaccharide and lipid A, and is displaced competitively by other compounds which possess affinity toward endotoxins. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
-20°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
参考文献
[1]. Huff T, et al. Thymosin beta(4) serves as a glutaminyl substrate of transglutaminase. Labeling with fluorescentdansylcadaverine does not abolish interaction with G-actin. FEBS Lett. 1999 Dec 24;464(1-2):14-20.
[2]. Laha D, et al. Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7. Biochim Biophys Acta. 2014 Jan;1840(1):1-9.
溶解度数据
In Vitro: DMSO : 62.5 mg/mL (186.31 mM; Need ultrasonic)H2O : 1 mg/mL (2.98 mM; ultrasonic and warming and heat to 80°C)配制储备液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2