(Z)-Capsaicin|25775-90-0|((Z)-辣椒素; Zucapsaicin; Civamide; cis-Capsaicin)-陌孚医药/Medlife

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(Z)-Capsaicin (Synonyms: (Z)-辣椒素; Zucapsaicin; Civamide; cis-Capsaicin)

目录号: PL12465 纯度: ≥99%

CAS No. :25775-90-0

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中文名称	(Z)-Capsaicin
中文别名	(Z)-辣椒素;(Z)-辣椒碱;(Z)-N-(4-羟基-3-甲氧基苄基)-8-甲基-6-壬烯酰胺;N-乙酰基-3-羟基吲哚;Z-辣椒素、珠卡赛辛;顺辣椒素;珠卡赛辛
英文名称	(Z)-Capsaicin
英文别名	(Z)-N-(4-Hydroxy-3-methoxybenzyl)-8-methylnon-6-enamide;8-Methyl-N-vanillyl-6-nonenamide;(Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide;Zucapsaicin;(Z)-Capsaicin;cis-Capsaicin;(Z)-8-Methyl-N-vanillyl-6-nonenamide;6-Nonenamide, N-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-, (Z)-;BRN 4261852;cis-8-methyl-N-vanillyl-6-nonenamide;Civamide;N-((4-Hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide (Z)-;Z-capsaicin;Zucapsaicin [USAN:INN];15OX67P384;CPD000449294;Civanex;(6Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide;SMR000449294;(Z)-N-[(4-hydroxy-3-methoxyphenyl)meth
Cas No.	25775-90-0
分子式	C₁₈H₂₇NO₃
分子量	305.41
包装储存	4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

产品详情

(Z)-Capsaicin 是 capsaicin 的顺式异构体，为可口服的 TRPV1 激动剂，可用于神经性疼痛的研究。

生物活性

(Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain.

性状

Solid

IC50 & Target[1][2]

TRPV1 receptor

体外研究(In Vitro)

(Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel. has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

(Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs. has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

ClinicalTrial

参考文献

[1]. Bourne N, et al. Civamide (cis-capsaicin) for treatment of primary or recurrent experimental genital herpes. Antimicrob Agents Chemother. 1999 Nov;43(11):2685-8.

溶解度数据	In Vitro: DMSO : ≥ 125 mg/mL (409.29 mM)配制储备液

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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