CL264
目录号: PL12342 纯度: ≥98%
CAS No. :1510712-69-2
商品编号 规格 价格 会员价 是否有货 数量
PL12342-5mg 5mg ¥4945.45 请登录
PL12342-10mg 10mg ¥8407.27 请登录
PL12342-25mg 25mg ¥16690.91 请登录
PL12342-50mg 50mg ¥27200.00 请登录
PL12342-100mg 100mg ¥43272.73 请登录
PL12342-200mg 200mg 询价 询价
PL12342-500mg 500mg 询价 询价
PL12342-10mM*1mLinDMSO 10mM*1mLinDMSO ¥5440.00 请登录
Medlife所售产品仅用于科学研究(非临床研究),非药品不可食用,不可用于人体或动物的临床诊断和治疗,我们不为个人提供产品及服务。产品COA等资料,可至下方“质量控制”中下载。
中文名称
CL264
英文名称
CL264
英文别名
CL264;Glycine,N-[4-[[6-amino-2-(butylamino)-7,8-dihydro-8-oxo-9H-purin-9-yl]methyl]benzoyl]
Cas No.
1510712-69-2
分子式
C19H23N7O4
分子量
413.43
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
CL264 是一种 TLR7 特异性激动剂,可用于先天免疫信号通路的研究。
生物活性
CL264 is a TLR7-specific agonist for innate immune signals research.
性状
Solid
IC50 & Target[1][2]
TLR7
体外研究(In Vitro)
Toll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs), macrophages and B cells. Many TLR7 modulators are interferon inducers, anti-cancer agents, anti-infectious agents, therapeutic agents for immunological diseases and vaccine adjuvants. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Butterfield JSS, et al. TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer. Hum Gene Ther Methods. 2019 Jun;30(3):81-92.
溶解度数据
In Vitro: DMSO : 25 mg/mL (60.47 mM; Need ultrasonic)配制储备液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2