1α-Hydroxy-3-epi-vitamin D3|58028-00-5|-陌孚医药/Medlife

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1α-Hydroxy-3-epi-vitamin D3

目录号: PL11898 纯度: ≥99%

CAS No. :58028-00-5

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中文名称	1α-Hydroxy-3-epi-vitamin D3
英文名称	1α-Hydroxy-3-epi-vitamin D3
英文别名	1alpha-hydroxy-3-epivitamin D3 / 1alpha-hydroxy-3-epicholecalciferol;1;A-Hydroxy-3-epi-vitamin D3;1alpha-Hydroxy-3-epivitamin D3;(1S,3S,Z)-5-((E)-2-((1R,3AS,7aR)-7a-Methyl-1-((R)-6-methylheptan-2-yl)hexahydro-1H-inden-4(2H)-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol;LMST03020232;(1S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-ind;1alpha-hydroxy-3-epivitamin D3/1alpha-hydroxy-3-epicholecalciferol;1α-Hydroxy-3-epi-vitamin D3
Cas No.	58028-00-5
分子式	C₂₇H₄₄O₂
分子量	400.64
包装储存	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

产品详情	1α-Hydroxy-3-epi-vitamin D3 是 1α，25-二羟基维生素 D3 的天然代谢物，是甲状旁腺激素 (PTH) 分泌的抑制因子。
生物活性	1α-Hydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone (PTH) secretion.
性状	Solid
体外研究(In Vitro)	1 alpha, 25(OH)2D3 is an important negative regulator of parathyroid hormone (PTH) gene transcription. In ROS 17/2.8 cells, 1α-OHD3 (10 μM) not only metabolized into 1αOH-3-epi-D3 and 1α,25(OH)2D3 but also 1α,25(OH)2-3-epi-D3. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献	[1]. A J Brown, et al. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion. J Cell Biochem. 1999 Apr 1;73(1):106-13. [2]. Alex J Brown, et al. Isolation and identification of 1alpha-hydroxy-3-epi-vitamin D3, a potent suppressor of parathyroid hormone secretion. J Cell Biochem

溶解度数据	In Vitro: DMSO : 50 mg/mL (124.80 mM; Need ultrasonic)配制储备液

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