Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia.
性状
Solid
体外研究(In Vitro)
Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability.Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells. has not independently confirmed the accuracy of these methods. They are for reference only.Cell Viability Assay
体内研究(In Vivo)
Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice. has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model: Female C57BL/6 mice are induced colitis by d
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
ClinicalTrial
参考文献
[1]. Ferrari P, et, al. Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: comparison between oral ferrous bisglycinate chelate and ferrous sulfate. Biomed Pharmacother. 2012 Sep; 66(6): 414-8.[2]. Yu X, et, al. Iron Transport from Ferrous Bisglycinate and Ferrous Sulfate in DMT1-Knockout Human Intestinal Caco-2 Cells. Nutrients. 2019 Feb 26; 11(3): 485.
溶解度数据
In Vitro: 0.1 M HCL : 2 mg/mL (9.90 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)配制储备液