Nequinate|13997-19-8|-陌孚医药/Medlife

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Nequinate

目录号: PL11685

CAS No. :13997-19-8

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中文名称	Nequinate
中文别名	甲氧苄喹酯;苄氧丁喹酮酯;苄氧喹甲酯;奈喹酯;CO-1686中间体3;WAKO147-09141甲氧苄喹酯标准品;甲氧苄喹酯标准品;甲氧苄喹酯,苄氧丁喹酮酯,苄氧喹甲酯;7-(苄氧基)-6-丁基-1,4-二氢-4-氧代-3-喹啉羧酸甲酯;萘喹酯;苄喹酸酯;甲氧喹酯;甲苄氧喹啉;苯甲氧喹啉;甲氧苄喹酯标准品
英文名称	Nequinate
英文别名	Methyl 7-(benzyloxy)-6-butyl-4-oxo-1,4-dihydroquinoline-3-carboxylate;methylbenzoquate nequinate;6-butyl-1,4-dihydro-4-oxo-7-(phenyl methoxy)-3-quinolinecarboxylic acid methyl ester;Statyl statil Statoquate Tranil;Nequinate;Nequinate (for Animal);Statyl;AY-20385;ICI-55052;Mequinate;Statoquate;Methyl benzoquat;MethylBenzoquate;Nequinate VETRANAL;methyl benzoquinate;Methyl benzoquate;Nequinato;Nequinatum;Nequinate (USAN);ICI 55052;Methyl 7-(benzyloxy)-6-butyl-1,4-dihydro-4-oxo-3-quinolinecarboxylate;AY 20385;91ZE013933;3-Quinolinecarboxylic acid, 6-butyl-1,4-dihydro-4-oxo-7-(phenylmethoxy)-, methyl ester;methyl 6-butyl-4-oxo-7-phenylmethoxy-1H-quinoline-3-carboxylate;Nequinate [USAN:INN];Nequinatum [INN-Latin];N;Methylbenzoquate nequinate;6-Butyl-1,4-dihydro-4-oxo-7-(phenyl methoxy)-3-quinolinecarboxylic acid methyl ester;NEQUINATE
Cas No.	13997-19-8
分子式	C₂₂H₂₃NO₄
分子量	365.42
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	Nequinate 是一种喹啉化合物，抗球虫试剂 (anticoccidial agent)，对抗盲肠球虫 (Eimeria tenella) 感染。Nequinate 抑制黄嘌呤氧化还原酶 (XOD) 活性。
生物活性	Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
IC50 & Target[1][2]	Coccidia
体外研究(In Vitro)	Xanthine oxidase (XOD) is a successful and safe drug target for lowering lower serum urate (sUA) levels , it plays an important role in the catabolism of purine Nequinate shows an inhibition of 12.0% to inhibit XOD activities. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. D K McLoughlin, et al.Efficacy of Nequinate Against Thirteen Strains of Eimeria Tenella and the Development of a Nequinate-Resistant Strain.Avian Dis. Oct-Dec 1973;17(4):717-21. [2]. Yanfen Niu, et al. Old Drug, New Indication: Olsalazine Sodium Reduced Serum Uric Acid Levels in Mice via Inhibiting Xanthine Oxidoreductase Activity. J Pharmacol Sci. 2017 Nov;135(3):114-120.

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