(±)-cis-Sertraline-d3 (hydrochloride)|1217741-83-7|((±)-盐酸舍曲林 d-陌孚医药/Medlife

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(±)-cis-Sertraline-d3 (hydrochloride) (Synonyms: (±)-盐酸舍曲林 d

目录号: PL11250

CAS No. :1217741-83-7

商品编号	规格	价格	会员价	是否有货	数量
PL11250-1mg	1mg	询价	询价
PL11250-10mg	10mg	询价	询价

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中文名称	(±)-cis-Sertraline-d3 (hydrochloride)
中文别名	[2H3]-舍曲林盐酸盐;(±)-CIS-SERTRALINE-D3 HYDROCHLORIDE (N-METHYL-D3);(±)-舍曲林-[D3]盐酸盐;(±)-盐酸舍曲林 d3 (盐酸盐)
英文名称	(±)-cis-Sertraline-d3 (hydrochloride)
英文别名	Sertraline-d3 Hydrochloride;(1S,4S)-4-(3,4-dichlorophenyl)-N-(trideuteriomethyl)-1,2,3,4-tetrahydronaphthalen-1-amine:hydrochloride;[2H3]- Sertraline Hydrochloride;(±)-cis-Sertraline-d3 hydrochloride (N-methyl-d3);(±)-cis-Sertraline-d3 HCl (N-methyl-d3);Sertraline hydrochloride salt;Sertraline-d3 HydrochlorideQ: What is Sertraline-d3 Hydrochloride Q: What is the CAS Number of Sertraline-d3 Hydrochloride;2H3]-Sertraline HCI;2H3]-Sertraline hydrochloride salt;(±)-cis-Sertraline-d3 (hydrochloride)
Cas No.	1217741-83-7
分子式	C₁₇H₁₈Cl₃N
分子量	345.71
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	(±)-cis-Sertraline-d₃ (hydrochloride) 是 Sertraline hydrochloride 的氘代物。Sertraline hydrochloride 是一种选择性 5- 羟色胺再吸收抑制剂 (SSRI) 类的抗抑郁剂。Sertraline hydrochloride 用于研究多种疾病，例如重度抑郁症和强迫症。
生物活性	(±)-cis-Sertraline-d 3 (hydrochloride) is the deuterium labeled Sertraline hydrochloride. Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive[1][2].
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Murdoch D, et al. Sertraline. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depression and obsessive-compulsive disorder. Drugs. 1992 Oct;44(4):604-24.

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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