Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Anti-SARS-CoV-2 Spike mAb (CR3022) 是一种 CHO 细胞来源的、人源的单克隆抗体 IgG1,与SARS-CoV/SARS-CoV-2 Spike蛋白 (S1) 结合。
生物活性
Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.
性状
Liquid
体外研究(In Vitro)
CR3022 recognizes a cryptic epitope that is only accessible when S protein is in “open” conformations. CR3022 binds more tightly to SARS-CoV because its epitope contains a glycan not present in SARS-CoV-2. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Yanling Wu, et al. Identification of Human Single-Domain Antibodies Against SARS-CoV-2. Cell Host Microbe. 2020 Jun 10;27(6):891-898.e5.[2]. Meng Yuan, et al. A Highly Conserved Cryptic Epitope in the Receptor Binding Domains of SARS-CoV-2 and SARS-CoV. Science. 2020 May 8;368(6491):630-633.