Urokinase (peptidolytic) (Synonyms: 尿激酶; Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase)
目录号: PL11229
CAS No. :9039-53-6
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中文名称
Urokinase (peptidolytic)
中文别名
尿激酶;尿激酶(从人体中提取);U-血纤维蛋白溶酶原激活剂;尿活素;尿激酶(人尿);雅激酶;UK粗品 尿激酶;Urolinase 尿激酶;尿激酶 来源人类尿液;尿酸酶;十一酸
英文名称
Urokinase (peptidolytic)
英文别名
Urokinase;EC 3.4.99.26;UROKINASE UPA 2-CHAIN;UROKINASE 2-CHAIN;UROKINASE, HIGH MOLECULAR WEIGHT;UROKINASE, HIGH MW (URINE);UROKINASE, LOW MW (URINE);UROKINASE (MIXED);Urokinase from human urine;UROKINASE STERILE FROM HUMAN URINE;Undecanoic acid;u-Plasminogen activator;Urokinase plasminogen activator;Cambendazole;Cambendazol;Novazole;Noviben;Bonlam;Cambenzole;Equiben;CBDZ;MK 905;Cambendazole-d7;079X63S3DU;5-BENZIMIDAZOLECARBAMIC ACID, 2-(4-THIAZOLYL)-, ISOPROPYL ESTER;NSC377071;N-(Thiazolyl-4)-2, benzimidazolyl-5, carbamate D'isopropyle;Camdan;Camvet;propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate;Carbamic acid, (2-(4-thiazolyl)-1H-benzimidazol-5-yl)-, 1-methylethyl ester;NOE [French];2-(4-Thiazolyl)-5-Isopropoxycarbony;Kinase (enzyme-activating), uro- (9CI);2-Chain urokinase;Abbokinase;Actosolv;Breokinase;Cytokinase;Double-chain urokinase-type plasminogen activator;E.C. 3.4.21.31;E.C. 3.4.21.73;E.C. 3.4.99.26;Persolv;Plasminokinase, urinary;PLAU;Pro-hepatocyte growth factor convertase;Pro-HGF convertase;Proteins, PLAU;Purochin;Two-chain urokinase;Two-chain urokinase-type plasminogen activator;Ukidan;Urokinase medac;Urokinase-like plasminogen activator;Urokinase-type plasminogen activator;Uronase;Win 22005;Win-Kinase
Cas No.
9039-53-6
分子式
C14H14N4O2S
分子量
302.35
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Urokinase peptidolytic (Urokinase-type plasminogen activator) 是一种丝氨酸蛋白酶,是丝氨酸蛋白酶纤溶酶的一种非活性形式(酶原)。纤溶酶的激活可触发蛋白水解级联反应,进而参与血栓溶解或细胞外基质降解,涉及血管疾病和癌症相关研究。
生物活性
Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research.
性状
Solid
体外研究(In Vitro)
Urokinase peptidolytic(uPA) 在非小细胞肺癌 (NSCLC) 中能够增加 uPAR 蛋白质和 mRNA 水平的表达。
has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Nunzia Montuori, et al. Urokinase-mediated posttranscriptional regulation of urokinase-receptor expression in non small cell lung carcinoma. Int J Cancer. 2003 Jun 20;105(3):353-60
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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