Azetidin-3-ol hydrochloride|18621-18-6|(3-羟基氮杂环丁烷盐酸盐)-陌孚医药/Medlife

您当前的位置：

Azetidin-3-ol hydrochloride (Synonyms: 3-羟基氮杂环丁烷盐酸盐)

目录号: PL10519 纯度: ≥98.0%

CAS No. :18621-18-6

商品编号	规格	价格	会员价
PL10519-500mg	500mg	¥432.73	请登录
PL10519-1g	1g	¥562.55	请登录
PL10519-5g	5g	询价	询价
PL10519-10g	10g	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Azetidin-3-ol hydrochloride
中文别名	3-羟基氮杂环丁二烯盐酸盐;3-羟基氮杂环丁烷盐酸盐;3-羟基吖啶盐酸盐;3-羟基杂氮环丁烷盐酸盐;3-羟基-氮杂环丁烷;3-羟基吖丁啶盐酸盐;3-羟基氮环丁烷盐酸盐;3-Hydroxyazetidine Hydrochloride 3-羟基氮杂环丁烷盐酸盐;3-羟基-N-杂环丁烷盐酸盐;3-羟基吡咯烷盐酸盐;3-羟基氮杂环丁烷盐酸盐,3-Hydroxyazetidine hydrochloride;3-羟基氮;3-氮杂环丁醇盐酸盐;吖啶叮-3-羟基;3-羟基环丁胺盐酸盐;3-羟基丫丁啶盐酸盐;氮杂环丁烷-3-羟基盐酸盐
英文名称	Azetidin-3-ol hydrochloride
英文别名	Azetidin-3-ol hydrochloride;3-AZETIDINOL HYDROCHLORIDE;3-HYDROXYAZETIDINE HCL;3-HYDROXYAZETIDINE HYDROCHLORIDE;BUTTPARK 75\04-67;AZETIDIN-3-OL, HYDROCHLORIDE SALT;AZETAN-2-ONE MA4E00860;3-(Hydroxy)azetidine hydrochloride;Azetidin-3-ol HCl;azetidin-3-ol,hydrochloride salt;azetidin-3-ol-hydrochloride;3-(hydroxy)azetidine;3-hydroxy-1-azetidine hydrochloride;3-hydroxyazetidine monohydrochloride;3-Hydroxyazetidine-HCl;3-hydroxyazetidinium chloride;azetidin-3-ol monohydrochloride;hydrochloride;AZETAN-2-ONE;3-hydroxyazatidine HCl;3-Hydroxyazetidine Hcl Salt;3-Hydroxyazetidine hydroc...;-Hydroxyazetidine hydrochloride;azetidin-3-ol hydrochloride salt;3-Azetidinol, hydrochloride;azetidine-3-ol hydrochloride;3-hydroxy-azetidine hydrochloride;PubChem12930;azetidin-3-ol, chloride;3-Hydroxyazetidine, HCl;3-Hydroxyazacyclobutane hydrochloride;3-Azetidinol Hydrochloride;AZETIDIN-3-OL HYDROCHLORIDE
Cas No.	18621-18-6
分子式	C₃H₈ClNO
分子量	109.55
包装储存	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	Azetidin-3-ol (hydrochloride) 是不可降解 (non-cleavable) 的 ADC linker，用于合成抗体偶联药物 (ADCs)。Azetidin-3-ol (hydrochloride) 也是一个基于烷基链 (alkyl chain) 的 PROTAC linker，可用于合成 PROTAC。
生物活性	Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidin-3-ol hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthes PROTAC.
性状	Solid
IC50 & Target[1][2]	Non-cleavable
体外研究(In Vitro)	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

溶解度数据	In Vitro: DMSO : 25 mg/mL (228.21 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation