3-IN-PP1|2227110-54-3|-陌孚医药/Medlife

您当前的位置：

3-IN-PP1

目录号: PL09909

CAS No. :2227110-54-3

商品编号	规格	价格	会员价
PL09909-5mg	5mg	¥2720.00	请登录
PL09909-10mg	10mg	¥4450.91	请登录
PL09909-25mg	25mg	¥8901.82	请登录
PL09909-50mg	50mg	¥14218.18	请登录
PL09909-100mg	100mg	询价	询价
PL09909-200mg	200mg	询价	询价

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	3-IN-PP1
英文名称	3-IN-PP1
英文别名	1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1H-indol-3-yl)-;3-IN-PP1
Cas No.	2227110-54-3
分子式	C₁₇H₁₈N₆
分子量	306.37
包装储存	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

产品详情	3-IN-PP1 是一种蛋白激酶 D (PKD) 抑制剂。 3-IN-PP1 对 PKD1、PKD2 和 PKD3 具有有效广泛的 PKD 抑制活性， IC₅₀ 值分别为 108、94 和 108 nM。3-IN-PP1 也是一种广谱抗癌剂，对多种肿瘤细胞的生长有抑制作用。3-IN-PP1 可用于癌症研究。
生物活性	3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC 50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer.
性状	Solid
IC50 & Target[1][2]	PKD1 108 nM (IC50) Cellular PKD2 94 nM (IC
体外研究(In Vitro)	3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 (5 μM, 0-114 h) displays potent anti-proliferative activity against PANC-1 cells. 3-IN-PP1 (20 μM, 1 h) potently blocks PKD-dependent cortactin phosphorylation in PANC-1 cells. 3-IN-PP1 has inhibition of different tumor cell growth with IC50 values range from 1.6 to 39.2μM. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献	[1]. Philippe Gilles, et al. Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors. Eur J Med Chem

溶解度数据	In Vitro: DMSO : 100 mg/mL (326.40 mM; Need ultrasonic)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation