Tanezumab
目录号: PL09104 纯度: ≥99%
CAS No. :880266-57-9
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中文名称
Tanezumab
中文别名
他尼珠;TANEZUMAB ( 他尼组单抗 );他尼组单抗
英文名称
Tanezumab
英文别名
Tanezumab;tanezumab;Research Grade Tanezumab(DHB91701);RN 624;PF 4383119
Cas No.
880266-57-9
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Tanezumab (RN-624) 是一种具有高亲和力和特异性的人源化抗 NGF 单克隆抗体,能阻断 NGF 与周围神经系统中的受体 p75 和 TrkA 结合。Tanezumab 可用于急性和慢性疼痛,如骨关节炎,膝关节和神经痛和带状疱疹后神经痛的研究。
生物活性
Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia.
性状
Liquid
IC50 & Target[1][2]
NGF.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
ClinicalTrial
参考文献
[1]. Evans M, et al. Effects of tanezumab on satellite glial cells in the cervicothoracic ganglion of cynomolgus monkeys: A 26-week toxicity study followed by an 8-week recovery period. Auton Neurosci. 2019 May;218:51-53.
[2]. Mantyh P, et al. a humanized anti-nerve growth factor antibody for the treatment of pain[J]. The Journal of Pain, 2009, 10(4): S44.
搜索质检报告(COA)

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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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