3,4,5-Trihydroxycinnamic acid decyl ester|1770778-45-4|-陌孚医药/Medlife

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3,4,5-Trihydroxycinnamic acid decyl ester

目录号: PL08590 纯度: ≥98%

CAS No. :1770778-45-4

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中文名称	3,4,5-Trihydroxycinnamic acid decyl ester
英文名称	3,4,5-Trihydroxycinnamic acid decyl ester
英文别名	3,4,5-Trihydroxycinnamic acid decyl ester;3-(3,4,5-Trihydroxyphenyl)propenoic acid decyl ester
Cas No.	1770778-45-4
分子式	C₁₉H₂₈O₅
分子量	336.42
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	3,4,5-Trihydroxycinnamic acid decyl ester 是一种高效的脂质吸收和积累抑制剂，具有抗肥胖作用。3,4,5-Trihydroxycinnamic acid decyl ester 是一种胰腺脂肪酶 (pancreatic lipase) 抑制剂，其 EC₅₀ 大约为 0.9 μM。
生物活性	3,4,5-Trihydroxycinnamic acid decyl ester is an excellent inhibitor of lipid absorption and accumulation, with anti-obesity properties. 3,4,5-Trihydroxycinnamic acid decyl ester is a pancreatic lipase inhibitor, with an EC 50 of approximately 0.9 μM.
性状	Solid
IC50 & Target[1][2]	EC50: 0.9 μM (pancreatic lipase)
体外研究(In Vitro)	3,4,5-Trihydroxycinnamic acid decyl ester (30 μM) exhibits an inhibitory potency of approximately 92% for pancreatic lipase in vitro. 3,4,5-Trihydroxycinnamic acid decyl ester (0.1-40 μM) inhibits pancreatic lipase activity in dose-dependent manner, with an EC50 value being approximately 0.9 μM. 3,4,5-Trihydroxycinnamic acid decyl ester inhibits pancreatic lipase in vitro and lipid accumulation during 3T3-L1 cell differentiation. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	3,4,5-Trihydroxycinnamic acid decyl ester (30-150 mg/kg; p.o.) suppresses a rise in blood triglyceride (TG) levels in mice given corn oil orally. has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Masahiko Imai ,et al. Inhibitory effects of hydroxylated cinnamoyl esters on lipid absorption and accumulation. Bioorg Med Chem. 2015 Jul 1;23(13):3788-95.

溶解度数据	In Vitro: DMSO : 100 mg/mL (297.25 mM; Need ultrasonic)配制储备液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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