Jagged-1 (188-204) TFA is a fragment of the Jagged-1 (JAG-1) protein with Notch agonist activity. JAG-1 is a Notch ligand highly expressed in cultured and primary multiple myeloma (MM) cells. JAG-1 induces maturation of monocyte-derived human dendritic cells.
性状
Solid
体外研究(In Vitro)
Jagged-1 (188-204) is part of the DSL region, and highly conserved between human Jagged-1 and Jagged-2. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
CDDYYYGFGCNKFCRPR
参考文献
[1]. Jundt F, et al. Jagged1-induced Notch signaling drives proliferation of multiple myeloma cells. Blood. 2004 May 1;103(9):3511-5.[2]. Weijzen S, et al. The Notch ligand Jagged-1 is able to induce maturation of monocyte-derived human dendriticcells. J Immunol. 2002 Oct 15;169(8):4273-8.[3]. Nickoloff BJ, et al.
溶解度数据
In Vitro: H2O : 50 mg/mL (22.51 mM; Need ultrasonic)配制储备液