Neurokinin A TFA (Synonyms: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA)
目录号: PL07730 纯度: ≥99%
CAS No. :2828433-19-6
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中文名称
Neurokinin A TFA
英文名称
Neurokinin A TFA
Cas No.
2828433-19-6
分子式
C52H81F3N14O16S
分子量
1247.34
包装储存
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
产品详情
Neurokinin A TFA (Substance K TFA) 是速激肽家族的一种肽类神经递质,通过 NK-2 受体发挥作用。在人气道和胃肠道组织中作为主要的介体。
生物活性
Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.
性状
Solid
体外研究(In Vitro)
Neurokinin A (substance K) is a peptide neurotransmitter of the tachykinin family with potential as a major mediator in human airway and gastrointestinal tissues. Neurokinin A acts via the NK-2 receptor believed to be localized on smooth muscle cells and pharmacologically coupled to a GTP-binding protein. Neurokinin A is a member of a family of peptide neurotransmitters known as tachykinins. These peptides are associated with the central and peripheral nervous systems and display a wide tissue distribution. Tachykinins share the COOH-terminal structure Phe-X-Gly-Leu-Met-NH. The best known members of this family are Substance P and Neurokinin A or Substance K. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
HKTDSFVGLM-NH2
Sequence
His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
参考文献
[1]. Gerard NP, et al. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. J Biol Chem. 1990 Nov 25;265(33):20455-62.
溶解度数据
In Vitro: DMSO : 100 mg/mL (80.17 mM; Need ultrasonic)H2O : 50 mg/mL (40.09 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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