Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase.
性状
Solid
体外研究(In Vitro)
Kynuramine 在体外抑制突触前和突触后 α-肾上腺素受体。Kynuramine 已被证明是狗脑动脉血清素受体的部分激动剂。Kynuramine (20 μg/mL) 经常导致回肠轻微收缩,但未能改变胆碱能刺激的抽搐反应。 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Kynuramine (0.064、0.32、1.6 或 8 μg;脑室内;单剂量) 可能在调节女性性行为中发挥生理作用。
Kynuramine (1.25、2.5 和 5.0 mg/kg;静脉注射;单剂量) 可增加髓内大鼠的心率和血压。 has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献
[1]. J B Massey, et al. Kynuramine, a fluorescent substrate and probe of plasma amine oxidase. J Biol Chem. 1977 Nov 25;252(22):8081-4.[2]. T D Johnson, An alpha-adrenoceptor inhibitory action of kynuramine. Eur J Pharmacol. 1981 Jul 10;72(4):351-6.[3]. S D Mendelson, et al. Intraventricular administration of l-ky
溶解度数据
In Vitro: DMSO : 125 mg/mL (527.14 mM; Need ultrasonic)配制储备液