Adrenocorticotropic Hormone (ACTH) (4-10), human
目录号: PL07053 纯度: ≥99%
CAS No. :4037-01-8
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中文名称
Adrenocorticotropic Hormone (ACTH) (4-10), human
中文别名
L-蛋氨酰-L-alpha-谷氨酰-L-组氨酰-L-苯丙氨酰-L-精氨酰-L-色氨酰甘氨酸
英文名称
Adrenocorticotropic Hormone (ACTH) (4-10), human
英文别名
Glycine, L-methionyl-L-a-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-;ACTH (4-10);ACTH (4-10), human;ADRENOCORTICOTROPIC HORMONE FRAGMENT 4-10;MET-GLU-HIS-PHE-ARG-TRP-GLY;[2-(3,4-dihydroxyphenyl)-2-oxoethyl]methylammonium chloride;1-(3,4-dihydroxy-phenyl)-2-methylamino-ethanone, hydrochloride;3',4'-Dihydroxy-2-(methylamino)acetophenone hydrochloride;adrenalon hydrochloride;ADRENALONE HCL;adrenalone*HCl;ADRENALONE, HYDROCHLORIDE;adrenocortical hormone (4-10);Adrenone hydrochloride;Epinephrine ketone hydrochloride;Kephrine hydrochloride;Antimicrobial peptide (unknown organism clone WO039857-SEQID-1266);Des-1-serine-des-2-tyrosine-des-3-serine-alpha1-10-corticotropin;Adrenocorticotropic Hormone (ACTH) (4-10), human
Cas No.
4037-01-8
分子式
C44H59N13O10S
分子量
962.09
包装储存
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
产品详情
Adrenocorticotropic Hormone (ACTH) (1-39), rat 是一种有效的黑皮质素 4 型受体 (melanocortin 4 receptor, MC4R) 激动剂。
生物活性
Adrenocorticotropic Hormone (ACTH) (4-10), human is a melanocortin 4 (MC4R) receptor agonist.
性状
Solid
IC50 & Target[1][2]
Melanocortin 4 receptor
体外研究(In Vitro)
Adrenocorticotropic Hormone (ACTH) (4-10), human (ACTH (4-10)) is the core sequence of all melanocortins and binds selectively to MC4-R. In humans, ACTH (4-10) enters the cerebral fluid compartment after intranasal application and leads to a decrease in total body fat after 6 weeks of continuous treatment. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
MEHFRWG
Sequence
Met-Glu-His-Phe-Arg-Trp-Gly
参考文献
[1]. Wellh?ner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8.
溶解度数据
In Vitro: DMSO : 25 mg/mL (25.99 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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