ACTH (11-24) (Synonyms: Adrenocorticotropic Hormone (11-24))
目录号: PL07063
CAS No. :4237-93-8
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中文名称
ACTH (11-24)
中文别名
促肾上腺皮质激素-(11-24)-十四肽
英文名称
ACTH (11-24)
英文别名
a11-24-Corticotropin;LogP;ACTH (11-24);ADRENOCORTICOTROPIC HORMONE FRAGMENT 11-24;Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro;Human ACTH(11-24);alpha11-24-ACTH;beta11-24-ACTH
Cas No.
4237-93-8
分子式
C77H134N24O16
分子量
1652.04
包装储存
Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years;-20°C 1 ye
产品详情
ACTH (11-24) 是一种促肾上腺皮质激素 (ACTH) 受体拮抗剂。ACTH (11-24) 是促肾上腺皮质激素的一个片段,可诱导皮质醇释放。ACTH(11-24)可用于中枢神经系统的研究。
生物活性
ACTH (11-24) is an adrenocorticotropic hormone (ACTH) receptor antagonist. ACTH (11-24) is a fragment of adrenocorticotropic and induces cortisol release. ACTH (11-24) can be used for the research of central nervous system.
性状
Solid
体外研究(In Vitro)
ACTH (11-24) elicits cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
ACTH (11-24) has slight influences on circulating plasma corticosterone values and on fighting behavior. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisture and light, under nitrogenPowder -80°C 2 years;-20°C 1 ye
SequenceShortening
KPVGKKRRPVKVYP
Sequence
Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
参考文献
[1]. Li ZG, et al. Adrenocorticotropin(1-10) and -(11-24) promote adrenal steroidogenesis by different mechanisms. Endocrinology. 1989 Aug;125(2):592-6.
[2]. P F Brain, et al. Acute influences of some ACTH-related peptides of fighting and adrenocortical activity in male laboratory mice. Pharmacol Biochem Behav
溶解度数据
In Vitro: H2O : 100 mg/mL (60.53 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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