Phenidone|92-43-3|(菲尼酮)-陌孚医药/Medlife

您当前的位置：

Phenidone (Synonyms: 菲尼酮)

目录号: PL06745 纯度: ≥98.0%

CAS No. :92-43-3

商品编号	规格	价格	会员价
PL06745-500mg	500mg	¥618.18	请登录
PL06745-1g	1g	询价	询价
PL06745-5g	5g	询价	询价
PL06745-10mM*1mLinDMSO	10mM*1mLinDMSO	¥618.18	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Phenidone
中文别名	1-苯基-3-吡唑烷酮;菲尼酮;1-苯基-3-吡唑酮;1-Phenyl-3-pyrazolidone 1-苯基-3-吡唑烷酮;菲尼酮,AR;菲尼酮,CP;菲尼酮A;1-苯基-3-氧-1,2-二氮杂茂;菲尼酮A,1-苯基-3-吡唑烷酮;菲尼酮 A
英文名称	Phenidone
英文别名	1-Phenylpyrazolidin-3-one;Phenidone A;1-Phenyl-3-pyrazolidino;Phenidone;1-Phenyl-3-pyrazolidone;1-Phenyl-3-pyrazolidinone;1-hydro-2-phenyl-pyrazol-5-one;1-P-3-P;1-phenyl-1H-pyrazolidin-3-one;1-phenyl-pyrazolidin-3-on;A PHENIDONE A;B PHENIDONE B;Fenidon;graphidone;N-phenylpyrazolidin-3-one;phenitone;PYRAZOLIDONE A;S PHENIDONE S;3-Pyrazolidinone, 1-phenyl-;Pyrazolidinone, 1-phenyl-;1-Phenyl-3-oxopyrazolidine;2-Pyrazolin-3-ol, 1-phenyl-;1-Phenyl-pyrazolidin-3-one;1-Phenylpyrazolid-3-one;1-phenyl-4,5-dihydro-1H-pyrazol-3-ol;MLS002639322;CMCWWLVWPDLCRM-UHFFFAOYSA-N;H0U5612P6K;Phenidone A (1-Phenyl-3-pyrazolidinone);Graphidone
Cas No.	92-43-3
分子式	C₉H₁₀N₂O
分子量	162.19
包装储存	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

产品详情	Phenidone 是一种具有口服活性的，环氧化酶 (COX) 和脂氧合酶 (LOX) 的双重抑制剂，可以改善实验性自身免疫性脑脊髓炎大鼠的瘫痪。Phenidone 是一种对自发性高血压大鼠有效的降压剂。Phenidone 用作照片显像剂。
生物活性	Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Phenidone is used as a photographic developer.
性状	Solid
IC50 & Target[1][2]	COX LOX
体外研究(In Vitro)	Phenidone significantly inhibits the increases in COX-1/-2 and 5-LOX in the spinal cords of rats with experimental autoimmune encephalomyelitis (EAE). has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	Phenidone inhibits the formation of vascular lipoxygenase products and to reduce blood pressure in the AII-dependent renovascular hypertensive rat. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献	[1]. Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035(2):206-210. [2]. Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6(1):52-58.

溶解度数据	In Vitro: DMSO : 100 mg/mL (616.56 mM; Need ultrasonic)H₂O : 3.33 mg/mL (20.53 mM; ultrasonic and warming and heat to 60°C)配制储备液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation