2'-Deoxy-5'-O-DMT-2'-fluorouridine|146954-74-7|-陌孚医药/Medlife

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2'-Deoxy-5'-O-DMT-2'-fluorouridine

目录号: PL06260 纯度: ≥99%

CAS No. :146954-74-7

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中文名称	2'-Deoxy-5'-O-DMT-2'-fluorouridine
中文别名	5'-O-[双(4-甲氧基苯基)(苯基)甲基]-2'-脱氧-2'-氟尿苷;2''-脱氧-5''-O-DMT-2''-氟尿苷;1-((2S,3s,4s,5s)-5-((双(4-甲氧基苯基)(苯基)甲氧基)甲基)-3-氟-4-羟基四氢呋喃-2-基)嘧啶-2,4(1h,3h)-二酮;2'-脱氧-5'-O-DMT-2'-氟尿苷;5''-O-[双(4-甲氧基苯基)(苯基)甲基]-2''-脱氧-2''-氟尿苷;5-O-[双(4-甲氧基苯基)(苯基)甲基]-2-脱氧-2-氟尿苷;DMT保护性-2'-氟脱氧尿苷;DMT保护性-2-氟脱氧尿苷;5'-DMT-2'-氟-2'-脱氧尿苷;5'-O-(4,4'-二甲氧基三苯甲基)]-2'-脱氧-2'-氟尿苷
英文名称	2'-Deoxy-5'-O-DMT-2'-fluorouridine
英文别名	5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-uridine;2'-Deoxy-5'-O-DMT-2'-fluorouridine;1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione;1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione;Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-;5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyuridine;5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorouridine;DMT-2'-F-dU;HG1172;1-((2R,3R,4R,5R);-5-((Bis(4-methoxyphenyl);5'-O-DMT-2'-Fluoro-2'-deoxyuridine;2'-Deoxy-5'-O-DMTr-2'-fluoro-uridine;2'-Deoxy-5'-O-DMT-2'-fluoro-D-uridine;5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-URIDINE;-3-fluoro-4-hydroxytetrahydrofuran-2-yl);2'-Deoxy-5'-O-DMT-2'-fluoro-uridine;Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]
Cas No.	146954-74-7
分子式	C₃₀H₂₉FN₂O₇
分子量	548.56
包装储存	4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

产品详情	2'-Deoxy-5'-O-DMT-2'-fluorouridine 是一种核苷类似物，是 5’-O-DMTr-5-FUDR 的衍生物。2'-Deoxy-5'-O-DMT-2'-fluorouridine 具有有效的抗黄热病 (YFV) 活性。
生物活性	2-Deoxy-5-O-DMT-2-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity.
性状	Solid
体外研究(In Vitro)	2-Deoxy-5-O-DMT-2-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2-Deoxy-5-O-DMT-2-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献	[1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35.

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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