Nitroflurbiprofen|158836-71-6|(硝基氟比洛芬; HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen)-陌孚医药/Medlife

您当前的位置：

Nitroflurbiprofen (Synonyms: 硝基氟比洛芬; HCT 1206; NO-flurbiprofen; Nitroxybutyl flurbiprofen)

目录号: PL06106 纯度: ≥99%

CAS No. :158836-71-6

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Nitroflurbiprofen
中文别名	nitroflurbiprofen;硝基氟比洛芬
英文名称	Nitroflurbiprofen
英文别名	[1,1'-Biphenyl]-4-aceticacid, 2-fluoro-a-methyl-,4-(nitrooxy)butyl ester;4-nitrooxybutyl 2-(3-fluoro-4-phenylphenyl)propanoate;AC1L3OPZ;Flurbinitroxybutylester;Flurbiprofen nitroxybutyl ester;HCT 1026;HCT 1206;HCT-1026;Nitroflurbiprofen;Nitroxybutyl flurbiprofen;NO-flurbiprofen;SureCN135465
Cas No.	158836-71-6
分子式	C₁₉H₂₀NO₅F
分子量	361.36
包装储存	Pure form -20°C 3 years；4°C 2 years

产品详情	Nitroflurbiprofen 是一种环氧合酶 (COX) 抑制剂。
生物活性	Nitroflurbiprofen is a cyclooxygenase (COX) inhibitor with nitric oxide (NO)-donating properties, modulates the increased intrahepatic vascular tone in portal hypertensive cirrhotic rats.
性状	Oil
IC50 & Target[1][2]	COX
体内研究(In Vivo)	In vivo hemodynamic measurements (n = 8/condition) and evaluation of the increased intrahepatic resistance by in situ perfusion (n=5/condition) are performed in rats with thioacetamide-induced cirrhosis that receive either Nitroflurbiprofen (45 mg/kg), Flurbiprofen (30 mg/kg, equimolar concentration to Nitroflurbiprofen), or vehicle by intraperitoneal injection 24 hours and 1 hour prior to the measurements. Treatment with Nitroflurbiprofen, an NO-releasing cyclooxygenase inhibitor, improves portal hypertension without major adverse effects in thioacetamide-induced cirrhotic rats by attenuating intrahepatic vascular resistance, endothelial dysfunction, and hepatic hyperreactivity to vasoconstrictors. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Pure form -20°C 3 years；4°C 2 years
参考文献	[1]. Laleman W, et al. Nitroflurbiprofen, a nitric oxide-releasing cyclooxygenase inhibitor, improves cirrhotic portalhypertension in rats. Gastroenterology. 2007 Feb;132(2):709-19.

搜索质检报告(COA)

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品