Vudalimab
目录号: PL06045 纯度: ≥99%
CAS No. :2329669-72-7
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中文名称
Vudalimab
英文名称
Vudalimab
英文别名
Vudalimab;Research Grade Vudalimab(DHH02222)
Cas No.
2329669-72-7
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Vudalimab 是一种有效的 PD-1 和 CTLA-4 双重抑制剂,是一种完全人源化的双特异性单克隆抗体。Vudalimab 靶向免疫检查点受体 PD-1 和 CTLA-4,促进肿瘤选择性 T 细胞激活。
生物活性
Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation.
性状
Liquid
体外研究(In Vitro)
XmAb20717 has binding avidity and contributes to T cell activation, including IL-2, CD45 cells, and IFNγ. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
XmAb20717 (every two days, for 16 d; NSG mice engrafted with KG1a-luc followed by engraftment with huPBMCs) enhances allogeneic anti-tumor responses in mice. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
ClinicalTrial
参考文献
[1]. Hedvat M, et, al. Dual Blockade of PD1 and CTLA4 with Bispecific Antibody XmAb20717 Promotes Human T Cell Activation and Proliferation.
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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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