Eculizumab (Synonyms: 依库珠单抗; Anti-Human C5, Humanized Antibody)
目录号: PL06039
CAS No. :219685-50-4
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中文名称
Eculizumab
中文别名
依库丽珠单抗;依库珠单抗;依库丽单抗;托西珠单抗;伊库利珠单抗;ECULIZUMAB ( 依库珠单抗 )
英文名称
Eculizumab
英文别名
Immunoglobulin,anti-(human complement C5 a-chain) (human-mouse monoclonal 5G1.1 heavy chain), disulfide withhuman-mouse monoclonal 5G1.1 light chain, dimer (9CI);eculizumab;h5G1.1;h5G1.1VHC+h5G1.1VLC;Soliris;Alexion;Eculizumab;H5G1.1;H5G1.1Vhc H5G1.1vlc;Unii-A3ulp0F556;ECULIZUMABUM;IMMunoglobulin,anti-(huMan coMpleMent C5 a-chain) (huMan-Mouse Monoclonal 5G1.1 heavy chain), disulfide withhuMan-Mouse Monoclonal 5G1.1 light chain, diMer (9CI)
Cas No.
219685-50-4
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Eculizumab (Anti-Human C5, Humanized Antibody) 是一种针对补体 C5 (complement C5) 的长效人源化单克隆抗体。Eculizumab 抑制 C5 裂解为 C5a 和 C5b,因此抑制末端补体系统的部署,包括膜攻击复合物 (MAC) 的形成。Eculizumab 具有用于溶血研究的潜力。
生物活性
Eculizumab (Anti-Human C5, Humanized Antibody) is a long-acting humanized monoclonal antibody targeted against complement C5. Eculizumab inhibits the cleavage of C5 into C5a and C5b and hence inhibits deployment of the terminal complement system including the formation of membrane attack complex (MAC). Eculizumab has the potential for haemolysis research.
性状
Liquid
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
ClinicalTrial
参考文献
[1]. Eline A Dubois,et al. Eculizumab. Br J Clin Pharmacol. 2009 Sep;68(3):318-9.
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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